Primary tuberculous pyomyositis is a rare manifestation of musculoskeletal tuberculosis especially in immunocompetent individuals without a focus of tuberculosis in the body and the underlying bone disease. It can cause a diagnostic dilemma for a physician and surgeon because of its similar presentation to soft tissue sarcomas, hematomas, and myopathies. We present a case of a 45-year-old immun...

The presence of Charcot-Leyden Crystals in liver biopsy is rare. A report case a 14-year-old boy who presented with persistent fever and respiratory symptoms. Chest X-ray CT thorax showed miliary infiltrates. Mantoux test was positive sputum for acid-fast bacilli (AFB) negative. patient started antitubercular therapy (ATT). There no response the still had fever. Further evaluation an ultrasound...

Tuberculosis is one of the most important infectious diseases. In 2009 estimate 9 million new cases were registered worldwide, mortality due tuberculosis reached 1.5 million (Markowski et al., 2011). Tuberculosis may infect any part of the body, but most commonly occurs in the lungs (known as pulmonary tuberculosis) (Dolin et al., 2010). Extra pulmonary TB occurs when tuberculosis develops outs...

PURPOSE To report an unusual presentation of tuberculosis. CASE REPORT A six-year old boy presented with left upper lid swelling of 15 days' duration and an asymptomatic midline neck mass from 2 months ago. Imaging studies, and microbiologic tests which demonstrated acid-fast bacilli in the fine needle aspirate of the thyroid mass, both confirmed a diagnosis of cold tuberculous thyroid absces...

Mycobacterium tuberculosis is the etiological agent of tuberculosis. The World Health Organization has estimated that 8 million of people develop active TB every year and the situation is complicated by an increase of Mycobacterium tuberculosis strains resistant to drugs used in antitubercular therapy: MDR and XDR-TB. Myrtle leaf extracts, used as an antiseptic in Sardinian traditional medicine...

New drugs active against drug-resistant tuberculosis are urgently needed to extend the range of TB treatment options to cover drug resistant infections. Quinoxaline derivatives show very interesting biological properties (antibacterial, antiviral, anticancer, antifungal, antihelmintic, insecticidal) and evaluation of their medicinal chemistry is still in progress. In this review we report the p...

Several new drugs have recently been developed for the treatment of tuberculosis (TB) and, together with a number of repurposed drugs, are currently in clinical trials. The challenge remains to determine which of these novel compounds to prioritize, and to identify which drug combinations will be most effective. The task of testing each novel drug in combination with both new and existing antit...