A new trinuclear oxo-centered chromium(III) complex with formula [Cr3O(CH3CO2)6(L)(H2O)2] (L = 5-hydroxyflavone, known as primuletin) was synthetized and characterized by ESI mass spectrometry, thermogravimetry, and 1H-NMR, UV-Vis, and FTIR spectroscopies. In agreement with the experimental results, DFT calculations indicated that the flavonoid ligand is coordinated to one of the three Cr(III) ...

Caffeic acid phenethyl ester (CAPE) is a bioactive component isolated from propolis. A series of CAPE analogues was synthesized and their antiradical/antioxidant effects analyzed. The effect of the presence of the double bond and of the conjugated system on the antioxidant effect is evaluated with the analogues obtained from 3-(3,4-dihydroxyphenyl) propanoic acid. Those obtained from 2-(3,4-di...

Juice prepared from lemon (Eureka), mandarin (Kinnow) and orange (Orlando) fruits cultivated in Saudi Arabia were analyzed for different physico-chemical properties, total phenolics, ascorbic acid and antiradical activities. Juices from lemon, mandarin and orange 8.97, 16.1 and 11.78% total soluble solids; 5.73, 1.37 and 1.69% titrable acidity; 79.21, 91.18 and 107.37 mg GAE/100mL total phenoli...

In this Density Functional Theory study, it became apparent that astaxanthin (ASTA) may form metal ion complexes with metal cations such as Ca⁺², Cu⁺², Pb⁺², Zn⁺², Cd⁺² and Hg⁺². The presence of metal cations induces changes in the maximum absorption bands which are red shifted in all cases. Therefore, in the case of compounds where metal ions are interacting with ASTA, they are redder in color...

Selected natural polyphenols, including ferulic acid (FA) and hesperetin (Hp) were tested for their antiradical activity using the stable radical DPPH•, as a first step to rank them according to their potency. Ranking also included quercetin (Qt), a very well-studied natural, polyphenolic antioxidant, and ascorbic acid (AA). All phenolics considered were also tested in binary mixtures with AA, ...

Background/Aim. Phytochemical and pharmacological investigations of essential oils isolated from plant species the genus Seseli have been intensified recently. These long-term use in nutrition traditional medicine treatment various disorders. Volatile secondary metabolites gracile Waldst. & Kit (Apiaceae) not pharmacologically examined so far. The aim conducted research was to assess antira...

In the current study, changes in health-promoting substances (phenolics and flavonoids) and antioxidant activity of carrot and mango beverages during storage at 25 and 35°C for 30, 60 and 90 days were investigated. The total phenolic content was determined using Folin–Ciocalteu method. The antioxidant activity was based on the evaluation of free–radical scavenging activity (FRSA) using DPPH rad...

Reactive oxygen species, along with reactive nitrogen species, may play an important role in the pathogenesis and progress of many diseases, including cancer, diabetes and sickle cell disease. It has been postulated that hydroxyurea, one of the main treatments in sickle cell disease, achieves its activity partly also through its antioxidant properties. A series of hydroxyurea derivatives of L- ...

Antioxidant capacity (AOC) against peroxyl radical and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS) radical cation was measured for a series of p-hydroxybenzoic (HB) and p-hydroxycinnamic (HC) acids at different pH. Quantum-chemical computation was performed using Gaussian 3.0 software package to calculate the geometry and energy parameters of the same compoun...

Twenty-four weaned female Hypor piglets (10.9 ± 0.1 kg mean BW) were used to evaluate the antioxidant effect of a natural extract, titrated in verbascoside, on blood and liver oxidative status in relation to a high intake of n-6 PUFA, inducing oxidative stress. Piglets were assigned to 1 of 3 experimental groups; the first group was fed a diet with 9% sunflower oil (T1) and the second received ...