Apomorphine in solution undergoes rapid autoxidation, producing greenish colored solutions, making it difficult to formulate as a stable pharmaceutical solution. To identify the optimum antioxidant agent/combination for apomorphine solution, a high performance liquid chromatography assay was used to study the stability of 50 μg/mL apomorphine HCI in 0.1% L-ascorbic acid (AA), 0.1% sodium metabi...

This study reports an evaluation of the free radical scavenging ability of a series of chromone derivatives, in the light of their structural features and conformational behaviour. The 2,2-diphenyl-1-picrylhydrazyl radical (DPPH˙) test for the assessment of radical scavenging properties was applied, and the interpretation of the experimental results was assisted by ab initio theoretical approac...

Natural and synthetic xanthone derivatives are well-known for their ability to act as antioxidants and/or enzyme inhibitors. This paper aims to present a successful synthetic methodology towards xanthenedione derivatives and the study of their aromatization to xanthones. Additionally their ability to reduce Fe(III), to scavenge DPPH radicals and to inhibit AChE was evaluated. The results demons...

Antibacterial and antioxidant effects of alcoholic extract for the Cucurbita pepo plant were studied. Properties optical (UV-visible spectrophotometer ) morphological surface(scanning electron microscopy detection was done, antibacterial activity investigated against pathogenic microbes (E.coli, Staphylococcus aureus). Results showed highest effect crud in growth E.coli by zone inhibition diame...

Damage to cell and tissues by oxidation of polyunsaturated fatty acids (PUFA) is one of the most important risk factors of many diseases such as atherosclerosis, roumatoid arthritis and cancer. Oxidation occurs due to increase of oxidant agents such as free radicals or decrease of antioxidants. Thymus daenensis Celak. is a herbaceous wild medicinal plant endemic to Iran. In the course of screen...

The present study describes in vitro antimicrobial and antioxidant activities of methanol extracts obtained from the leaves and twigs of the plant Daphne cneorum L. The antimicrobial activity of these extracts was tested against human pathogenic microorganisms using a minimum inhibitory concentration (MIC) values. Total phenolics and flavonoids, as well as the antioxidant activity of the extrac...

BACKGROUND Antimutagenic activity of plant extracts is important in the discovery of new, effective cancer preventing agents. There is increasing evidence that cancer and other mutation-related diseases can be prevented by intake of DNA protective agents. The identification of antimutagenic agents present in plants presents an effective strategy to inhibit pathogenic processes resulting from ex...

Since ancient people, mushroom have been used as a source of food and in therapeutic remedies. Many recent studies confirm different biological activities mushrooms which include antioxidant, antimicrobial, anticancer, antidiabetic anti-inflammatory activities. species evaluated for their This study highlights the effectiveness agents.

A limited number of mosses have ever been studied in regard to antioxidant activity, with only a few belonging to the European species. As part of our ongoing screening of bryophytes as natural antioxidant resources, a relevant biological activity investigation was conducted on three moss species, namely Brachythecium rutabulum (Hedw.) Schimp. (Brachytheciaceae), Calliergonella cuspidata (Hedw....

Lupin (Lupinus termis) seeds are popularly edible and used as snacks in Sudan. The current study aimed to evaluate some biological properties of the Sudanese lupin seeds such as the phytochemical constituents, the antimicrobial and antioxidant activities. The study revealed that the methanolic extract of lupin seeds have no significant antimicrobial activity against all the tested bacteria (6 d...