The aqueous extract of yerba mate, a South American tea beverage made from Ilex paraguariensis leaves, has demonstrated bactericidal and inhibitory activity against bacterial pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). The gas chromatography-mass spectrometry (GC-MS) analysis of two unique fractions of yerba mate aqueous extract revealed 8 identifiable small molecul...

Some new 3-[(5-benzylidene-2-phenyl)-3, 5-dihydro-4-H-imidazol-4-one-3-(4-bezoylhydrazono)]-indole-2-ones (VIII) have been synthesized from different isatinhydrazones (II) by condensing with 2-phenyl-5-benzylidene- 3-N (4-acetyl phenyl)-1, 5-dihydro-imidazol-4-one (VII). Their chemical structures have been confirmed by IR, 1HNMR, MASS and by elemental analysis. Investigation of antimicrobial ac...

The emergence of antibiotic-resistant pathogenic bacteria has given rise to the needs of antimicrobial compounds that derived from natural products which less likely to cause pathogen resistance. The most profound and traditional example of the antimicrobial from the nature is antimicrobial peptides (AMPs) that serve as natural innate barriers limiting microbial infection or act as an integral ...

conclusions the present study confirms the notion of selecting endophytic fungi of medicinal plant justicia for the bioassay-guided isolation of its bioactive compounds, and demonstrates that endophytic fungus chaetomium sp. nf15 could be a potential source of bioactive metabolites materials and methods endophytic fungi associated with the j. adhatoda l. plant were isolated from healthy plant p...

many medical properties including antimicrobial, anticancer, antioxidant, anti-inflammatory, etc. have been mentioned for Viola odorata. results have shown the solid cell-killing effects of Viola odorata cycloidal compounds. In addition, Pathogen resistance has necessitated the study of new antimicrobial compounds. This study aimed to evaluate the antimicrobial and anticancer effects of aqueous...

Some new 3-[(5-benzylidene-2-phenyl)-3, 5-dihydro-4-H-imidazol-4-one-3-(4-bezoylhydrazono)]-indole-2-ones (VIII) have been synthesized from different isatinhydrazones (II) by condensing with 2-phenyl-5-benzylidene- 3-N (4-acetyl phenyl)-1, 5-dihydro-imidazol-4-one (VII). Their chemical structures have been confirmed by IR, 1HNMR, MASS and by elemental analysis. Investigation of antimicrobial ac...

The increasing resistance of Campylobacter to clinically important antibiotics, such as fluoroquinolones and macrolides, is a serious public health problem. The objective of this study is to investigate synergistic anti-Campylobacter jejuni activity of fluoroquinolones and macrolides in combination with phenolic compounds. Synergistic antimicrobial activity was measured by performing a checkerb...

conclusions optimization of medium composition and synergistic antimicrobial activity on the cyanobacteria could lead to production of effective antimicrobials. results c. leptolyngbya had antimicrobial activity individually and in synergy with antibiotics against gram-positive and gram-negative bacteria. the highest activity of the chloroform extract was on gram positive strains and its effect...

Benzimidazole derivates play vital role in biological field such as antimicrobial, antiviral, antidiabetic, and anticancer activity. Therapeutic significance of these clinically useful drugs in treatment of microbial infections encouraged the development of some more potent and significant compounds. With the purpose of finding new chemical entities with enhanced antimicrobial activity, a serie...