There is increasing resistance of malaria parasites to chloroquine, the cheapest and commonly used drug for malaria in Nigeria. Artemisin, a product from medicinal plant indigenous to China, based on active principle of Artemisia annua, has been introduced into the Nigerian market. However not much has been done to project antimalaria properties of indigenous medicinal plants. This study thus, ...

Background and objectives: There are several methods to assess the in vitro capability of heme inhibitory activity of antimalarial compounds; most of them require some specific equipment or toxic substances and sometimes the needed materials are not accessible. Regarding the necessity and importance of optimizing and standardizing experimental conditions, the present s...

BACKGROUND An unceasing threat of drug resistance continuously poses demand for new antimalarial drugs. A scientific assessment of traditionally used antimalarial plants through reverse pharmacology is crucial for a fast track drug discovery. An Ayurvedic plant Nyctanthes arbor-tristis Linn. - (Parijat) is being used in clinical practice and had shown antimalarial activity, with a parasite clea...

Endophytic bacteria are that live in plant tissue without causing negative effects. can produce bioactive compounds be used as antibacterial, anti-fungal, antiviral, anti-cancer, anti-diabetic, antimalarial and anti-immunosuppressive properties. found all higher plants, one of which is balakacida (Chromolaena odorata). This study aims to isolate the endophytic from Banda Aceh, test antimicrobia...

The recent development of new gold(I) catalysis methodologies has opened the door to new disconnections for the total synthesis of bioactive complex molecules. Below is described the application of a gold(I)-catalyzed hydroarylation of an allene with indole toward the total synthesis of flinderoles B-C, members of a new class of antimalarial bisindole alkaloids isolated from plants of the Flind...

Christia vespertilionis (L. f.) Bakh. f., (Family: Fabaceae), commonly known as ‘Red butterfly wing’ is an important medicinal plants with promising antimalarial and anticancer properties. The plant has been enlisted under the IUCN Red list of Threatened Species. A through literature survey available from all possible scientific sources revealed very little information about this plant. There r...