Malaria vector Anopheles and other mosquitoes (Diptera: Culicidae) were monitored for 12 months during 1994-95 in villages of Lower Moshi irrigation area (37 degrees 20' E, 3 degrees 21' S; approximately 700 m a.s.l.) south of Mount Kilimanjaro in northern Tanzania. Adult mosquito populations were sampled fortnightly by five methods: human bait collection indoors (18.00-06.00 hours) and outdoor...

The objective of this study is to investigate S.hermanni's antimalarial action against PfHT1 utilizing an in silico technique. In method, developing a protein target database by searching and collecting the structures from Protein Data Bank (PDB) UNIPROT databases. (PDB ID 6m20) with glucose control. Download all ligand PubChem database. Molecular docking analysis Molegro virtual docker predict...

Abstract Malaria remains a major cause of mortality in the world and an efficient vaccine is best chance reducing disease burden. Vaccination strategies for liver stage that utilise injection live radiation‐attenuated sporozoites (RAS) confer sterile immunity, which mediated by CD8 + memory T cells, with liver‐resident cells (T RM ) being particularly important. We have previously described TCR...

Abstract Modification of the adsorbent surfaces has been considered a fascinating strategy that enhances biomass-based adsorption properties for efficient removal organic pollutants. This is based on attempt to replace cost-ineffectiveness commercial activated carbon. The present study discusses different modification strategies and review modified biomass materials sorption contaminants. Unlik...

Aided by the Plasmodium falciparum genome project, recent discoveries regarding the molecular basis of malaria pathogenesis have led to a better understanding of the interactions between host and parasite. Although vaccines that prevent infection by malaria parasites remain only hopes for the future, there are now more immediate prospects for vaccines that protect against specific disease syndr...

BACKGROUND Mefloquine is a clinically important antimalaria drug, which is often not well tolerated. We critically reviewed 516 published case reports of mefloquine adverse effects, to clarify the phenomenology of the harms associated with mefloquine, and to make recommendations for safer prescribing. PRESENTATION We postulate that many of the adverse effects of mefloquine are a post-hepatic ...

Malaria parasitemia was assessed in 37 known sickle cell anemia patients attending the routine hematological clinic of the University of Benin Teaching Hospital, Benin-City, Edo State. Parasitemia was determined using the quantitative buffy coat analysis. The prevalence of malaria parasitemia among the population studied was 86.5%. There was no significant difference in the prevalence of parasi...