rose promptly and treatment was restarted within a month. Among essential hypertensive patients, those who remained off treatment for 2 to 6 months had significantly lower pretreatment pressure than those whose hypertension returned in less than 2 months. The two whose diastolic hypertension seemed "cured" had no distinguishing features. These results suggest that most hypertensive patients req...

Antihypertensive drugs are among the most prescribed drugs. Olmesartan acid, of sartan class, belongs to a relatively new generation antihypertensive called angiotensin II receptor blockers. There very few studies on presence and fate sartans in environment, despite them being marketed huge quantities, metabolized low percentages, detected wastewater water bodies. This paper presents study less...

BACKGROUND Evaluation of secondary stroke prevention in low and middle-income countries remains limited. This study assessed the prescription of secondary preventive drugs among ischemic stroke patients upon hospital discharge in Malaysia and identified factors related to the prescribing decisions. METHODS From Malaysian National Stroke Registry, we included patients with non-fatal ischemic s...

THE DRAMATIC DECLINE IN STROKE incidence in North America (approximately 60% in the past 15 years) has provoked much debate about the reasons for the decline. The role of the treatment of blood pressure in the reduction of stroke in general, and intracerebral hemorrhage in particular, has been a focus of the debate. Our recent experience highlights the need to pay attention, in future, to those...

BACKGROUND In a meta-analysis, we investigated the effects of angiotensin receptor blockers (ARBs) in comparison to placebo or other classes of antihypertensive drugs on endothelial function, which was measured by brachial flow-mediated vasodilation (FMD). METHODS We searched for randomized controlled trials that compared ARBs with placebo or other classes of antihypertensive drugs in improvi...