Diffuse alveolar hemorrhage (DAH) is a rare and potentially deadly complication of systemic lupus erythematosus (SLE). We report two adult cases where extracorporeal membrane oxygenation (ECMO) was used as rescue therapy for severe respiratory failure in this setting. We discuss the risk related to coagulation disturbance and the need for the circuit anticoagulation in this particular setting. ...

Anticoagulation of cerebral sinovenous thrombosis (CSVT) is recommended in adults and has been also approved in the paediatric setting. Some controversies remain however between the existing paediatric professional consensus, notably about its use in children with intra-cranial haemorrhage and in neonates. The publication of further original studies prompted the French Society for Paediatric Ne...

In this paper, we reviewed the atrial fibrillation screening strategies in a stepwise manner and discussed the uncertainties in the assessment of the need for anticoagulation in light of the recently published European Heart Rhythm Association consensus document. We reviewed not only the methods and tools but also the role of health care professionals and patient organizations in addition to co...

background: anticoagulation therapy is a routine treatment in patients with hemorrhagic cerebral venous thrombosis (cvt). however, fear of hemorrhagic complications and deterioration course following anticoagulation often disturbs the responsible physician. methods: this was a prospective observational study on consecutive cvt patients with hemorrhagic venous infarction or subarachnoid hemorrha...

This paper considers the risk assessment in the field of knowledge management. Since knowledge management systems can be observed at the stage of implementation and use, the risks also differ. An overview of the factors critical to the success of a knowledge management system is presented, as well as one method of risk assessment including its possible application to a knowledge management syst...

BACKGROUND There is growing evidence that kidney disease affects hepatically cleared drugs. Accordingly, we hypothesized that chronic kidney disease (CKD) would disrupt anticoagulation of warfarin-treated patients and thereby increase the amount of management required to maintain appropriate anticoagulation. Specifically, we anticipated that more dose manipulations (both dose changes and transi...

Oral anticoagulant therapy has been shown to be effective for several indications. The optimal intensity of anticoagulation for each indication, however, is largely unknown. To determine this optimal intensity, randomised clinical trials are conducted in which two target levels of anticoagulation are compared. This approach is inefficient, since the choice of the target levels will be arbitrary...

Background: Concern is growing about the malnutrition, nutrition therapy and its complications. Reduced involvement of nurses in patients’ nutritional care may be one of the contributing factors. The most common cause for insufficient nutritional practice is lack of nutritional knowledge. The purpose of the study was to determine knowledge-based nutrition competencies of nurses. Method and Mate...

Effective risk assessment and risk management approaches in public drinking water systems can benefit from a systematic process for hazards identification and effective management control based on the Water Safety Plan (WSP) concept. Good results from WSP development and implementation in a small number of Portuguese water utilities have shown that a more ambitious nationwide strategic approach...

OBJECTIVE Oral anticoagulation (OAC) is state-of-the-art therapy for atrial fibrillation (AF), the most common arrhythmia worldwide. However, little is known about the perception of patients with AF and how it correlates with risk scores used by their physicians. Therefore, we correlated patients' estimates of their own stroke and bleeding risk with the objectively predicted individual risk usi...