Multidrug-resistant pathogens are an emerging global health problem. In addition to the need of developing new antibiotics in the pipeline, the ability to rapidly determine the antibiotic resistance profiles of bacteria represents one of the most crucial steps toward the management of infectious diseases and the prevention of multidrug-resistant pathogens. Here, we report a single cell antimicr...

The untreated surface water for drinking and domestic use is an alarming situation to public health especially in prevalence of antibiotics resistant bacteria. This investigation aimed to isolate and identify the antibiotic resistance bacteria in underground water samples in district Dera Ismail Khan, Pakistan. The underground water samples were collected from four different places using hand p...

Antibiotic-resistant bacterial infections result in higher patient mortality rates, prolonged hospitalizations, and increased health care costs. Extensive use of antibiotics as growth promoters in the animal industry represents great pressure for evolution and selection of antibiotic-resistant bacteria on farms. Despite growing evidence showing that antibiotic use and bacterial resistance in fo...

Metabolite-enabled killing of antibiotic-resistant pathogens by antibiotics is an attractive strategy to manage antibiotic resistance. Our previous study demonstrated that alanine or/and glucose increased the killing efficacy of kanamycin on antibiotic-resistant bacteria, whose action is through up-regulating TCA cycle, increasing proton motive force and enhancing antibiotic uptake. Despite the...

Kon K. 2015. Prevalence of multidrug resistant bacteria in General Surgery Hospital, Ukraine. Nusantara Bioscience 7: 102106. Rising antibiotic resistance is a serious concern worldwide and during prescribing antibiotic treatment it is important to know general and regional tendencies in spread of multidrug resistant strains. The aim of the present study was to evaluate regional specificity of ...

chronic urinary tract infections are often caused by antibiotic resistant bacteria. in some of these cases, prediction of the most effective antibiotic (s) may urgently be needed. this can not be achieved unless the nature and patterns of the resistance to antibiotics among the pathogenic bacteria has been described earlier. the urine samples that reached the laboratory of shaheed mustafa khome...

Antimicrobial resistance has emerged as an important variable influencing patient mortality and overall resource use in the hospital setting (1). Intensive care units (ICUs) worldwide are faced with increasingly rapid emergence and spread of antibiotic-resistant bacteria. Both antibiotic-resistant Gramnegative and Gram-positive bacteria are reported as important causes of hospital-acquired infe...

OBJECTIVES To identify the antibiotics potentially the most involved in the occurrence of antibiotic-resistant bacteria from an ecological perspective in French healthcare facilities (HCFs). METHODS This study was based on data from the French antimicrobial surveillance network (ATB-RAISIN, 2007-09). Antibiotics were expressed in defined daily doses per 1000 patient-days. Antibiotic-resistant...

background: treatment of chronic sinusitis is complicated due to increase of antibiotic-resistant bacteria. the aim of this study was to determine the multidrug resistance (mdr) pattern of the bacteria causing chronic sinusitis in north of iran. methods: this cross-sectional study was carried out on patients with chronic sinusitis. bacterial susceptibility to antimicrobial agents was determined...

High antibiotic resistance frequencies have become a major public health issue. The decrease in new antibiotics' production, combined with increasing frequencies of multi-drug resistant (MDR) bacteria, cause substantial limitations in treatment options for some bacterial infections. To diminish overall resistance, and especially the occurrence of bacteria that are resistant to all antibiotics, ...