نتایج جستجو برای: anti mutagenicity
تعداد نتایج: 365747 فیلتر نتایج به سال:
The syn- and anti-isomers of the bay-region diol-epoxides of chrysene and of 3-hydroxychrysene and their metabolic precursors have been investigated for mutagenicity in Salmonella typhimurium (reversion to histidine prototrophy) and V79 Chinese hamster cells (acquirement of resistance to 6-thioguanine) and for transforming activity in M2 mouse prostate cells. Other known and potential chrysene ...
Seventeen samples of tap water in Bangkok and 2 neighboring provinces were collected in winter and summer, concentrated and tested for mutagenic activity using the Ames Salmonella mutagenesis assay. Preliminary results demonstrated that concentrated tap water exhibited clear mutagenicity towards S. typhimurium TA100 and YG1029, but not towards TA98 and YG1024, in the absence of S9 mix, and the ...
BACKGROUND Semen armeniacae amarum (SAA) is a Chinese traditional medicine and has long been used to control acute lower respiratory tract infection and asthma, as a result of its expectorant and antiasthmatic activities. However, its mutagenicity in vitro and in vivo has not yet been reported. The Ames test for mutagenicity is used worldwide. The histidine contained in biological samples can i...
در مواردی سیستم ایمنی بدن باعث بروز بیماریهای ایمنی مانند آنمی همولتیک نوزادان hdn می شود. تنها راه پیشگیری ایزوایمونیزاسیون rh ، ،تجویز پارتابولین (anti-d) به مادران rh منفی بعد از تولد نوزاد rh مثبت می باشد. پیشگیری از آلوایمونیزاسیون ناشی از ترانسفوزیون و درمان itp از دیگر اندیکاسیونهای تجویز anti-d می باشد. روش acid elution برای شناسایی میزان fmh جهت تصحی...
mebudipine is a new dihydropyridine calcium channel blocker, synthesized in our laboratory, for treatment of hypertension. it has shown a better efficacy than other drugs in this group. for assessing the risks of this drug, certain safety tests in the preclinical stage have been performed. in this study mutagenic effect of mebudipine was evaluated using ames assay that could assess the mutageni...
در این برنامه 229 نفر از افراد زیر 30 سال در زابل انتخاب شدند و نمونه خون جهت بررسی igg anti hav گرفته شد و جهت انجام آزمایش نمونه ها با حفظ زنجیره سرما به سازمان انتقال خون زاهدان فرستاده شد. در این بررسی از 229 نفر 117 نفر مونث (51/1 درصد) و 112 نفر مذکر (48/9 درصد) بودند. از کل جمعیت 203 نفر از نظر igg anti hav مثبت بودند (88/6 درصد) و 26 نفر igg anti hav در آنها منفی بود. فراوانی عفونت hav ...
Chemical mutagens with an aromatic ring system may be enzymatically transformed to afford aryl radical species that preferentially react at the C8-site of 2'-deoxyguanosine (dG). The resulting carbon-linked C8-aryl-dG adduct possesses altered biophysical and genetic coding properties compared to the precursor nucleoside. Described herein are structural and in vitro mutagenicity studies of a ser...
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