نتایج جستجو برای: anti biofilm

تعداد نتایج: 384868  

2015
Zhejun Wang Cesar de la Fuente-Núñez Ya Shen Markus Haapasalo Robert E. W. Hancock Zezhang Wen

Human oral biofilms are multispecies microbial communities that exhibit high resistance to antimicrobial agents. Dental plaque gives rise to highly prevalent and costly biofilm-related oral infections, which lead to caries or other types of oral infections. We investigated the ability of the recently identified anti-biofilm peptide 1018 to induce killing of bacterial cells present within oral m...

Journal: :The Journal of general and applied microbiology 2017
Marwa Jardak Faten Abdelli Rahma Laadhar Raphael Lami Didier Stien Sami Aifa Sami Mnif

The bacterial diversity associated with biofilm-forming ability was studied. Eighteen bacterial strains were isolated from a microbial film collected from the roof of an old house located in Sfax, Tunisia. The purity of these microorganisms was confirmed by microscopic observation after repeated streaking on a Tryptic Soy agar medium. Biofilm formation was estimated using preliminary tests incl...

Journal: :Nanoscale 2014
Lizeng Gao Krista M Giglio Jacquelyn L Nelson Holger Sondermann Alexander J Travis

Hydrogen peroxide (H2O2) is a "green chemical" that has various cleaning and disinfectant uses, including as an anti-bacterial agent for hygienic and medical treatments. However, its efficacy is limited against biofilm-producing bacteria, because of poor penetration into the protective, organic matrix. Here we show new applications for ferromagnetic nanoparticles (Fe3O4, MNPs) with peroxidase-l...

Journal: :Molecular bioSystems 2014
Chandrabose Selvaraj Jeyachandran Sivakamavalli Baskaralingam Vaseeharan Poonam Singh Sanjeev Kumar Singh

Enterococcus faecalis is a pathogenic Gram-positive bacterium, which mainly infects humans through urinary tract infections. SrtA is an essential enzyme for survival of E. faecalis, and inhibition of this particular enzyme will reduce the virulence of biofilm formation. It is proved to be associated with the microbial surface protein embedded signal transduction mechanism and promising as a sui...

Journal: :Organic & biomolecular chemistry 2015
Stefanie-Ann Alexander Caroline Kyi Carl H Schiesser

A series of 23 nitroxides () was tested for biofilm modulatory activity using a crystal violet staining technique. 3-(Dodecane-1-thiyl)-4-(hydroxymethyl)-2,2,5,5-tetramethyl-1-pyrrolinoxyl () was found to significantly suppress biofilm formation and elicit dispersal events in both Pseudomonas aeruginosa and mixed-culture biofilms. Twitching and swarming motilities were enhanced by nitroxide , l...

2015
Saad Musbah Alasil Rahmat Omar Salmah Ismail Mohd Yasim Yusof

Quorum sensing (QS) is a key regulator of virulence factors and biofilm formation in Gram-negative bacteria such as Pseudomonas aeruginosa. Microorganisms that inhabit soil are of strategic importance in the discovery of compounds with anti-QS properties. The objective of the study was to test the culture extract of a taxonomically novel species of Paenibacillus strain 139SI for its inhibitory ...

Journal: Current Medical Mycology 2016

Background and Purpose: Today, treatment of life-threatening fungal infections, caused by Candida species, has become a major problem. In the present study, we aimed to evaluate the antifungal susceptibility patterns of different clinical Candida isolates, determine the virulence factors in multi-drug resistant (MDR) Candida species, and assess the anti-biofilm activity of Elettaria cardamomum ...

2017
Juliana M. Ansari Nabil M. Abraham Jenna Massaro Kelsey Murphy Jillian Smith-Carpenter Erol Fikrig

Streptococcus mutans is the primary agent of dental cavities, in large part due to its ability to adhere to teeth and create a molecular scaffold of glucan polysaccharides on the tooth surface. Disrupting the architecture of S. mutans biofilms could help undermine the establishment of biofilm communities that cause cavities and tooth decay. Here we present a synthetic peptide P1, derived from a...

Background and aim: Excessive use of antibiotics has significantly increased resistance to common antibiotics in the treatment of urinary tract infections. In the present study, antimicrobial efficacy of chitosan nanoparticles and peptide IDR-1018 was evaluated against P. aeruginosa isolates. Methods: In the present study, 20 resistant and 20 sensitive P. aeruginosa isolates to imipenem were ...

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