OBJECTIVE to compare psychotropic prescribing in older people with dementia and the general elderly population. DESIGN AND SETTING retrospective population database study in 315 General Practices. SUBJECTS there were 271,365 patients aged > or = 65, of which 10,058 (3.7%) recorded as having dementia. METHODS epidemiology of psychotropic prescribing in older people with and without dementi...

BACKGROUND Mental disorders among older adults are mainly treated with psychotropic drugs. Few of these drugs are, however, prescribed by specialized geriatricians or psychiatrists, but rather from general practitioners (GPs). Socioeconomic inequalities in access to specialist prescribing have been found in younger age groups. Hence, we aimed to investigate whether there are socioeconomic diffe...

OBJECTIVE The objective of this study is to examine how nursing homes changed their use of antipsychotic and other psychoactive medications in response to Nursing Home Compare's initiation of publicly reporting antipsychotic use in July 2012. RESEARCH DESIGN AND SUBJECTS The study includes all state recertification surveys (n = 40,415) for facilities six quarters prior and post the initiation...

OBJECTIVE To evaluate the use of a therapeutic regimen to treat attention deficit hyperactivity disorder patients. METHODS A total of 140 patients initially underwent physical, neurological and laboratory evaluation. Thereafter, treatment was initiated with a compounding product consisting of a tricyclic antidepressant and an anxiolytic. RESULTS The response was positive in 71.43% of patien...

[This corrects the article DOI: 10.1371/journal.pone.0158779.].

OBJECTIVE To investigate the pattern and trends of use of antipsychotics, antidepressants, hypnotics and anxiolytics in Alzheimer's disease and other dementias and in patients treated with antidementia medications. DESIGN Cohort study with dementia patients formed in the UK Clinical Practice Research Datalink. Participants Patients with incident dementia, between 1995 and 2011 and a reference...

According to the National Institute of Statistics, Geography and Computer Sciences (INEGI, Spanish acronym), in 2003, the method employed in suicide attempts was mostly drug ingestion. The ratio of adolescent boys and girls between 10 and 14 years old involved in suicide attempt is 1:1.3, while the ration of those in the same age range that successfully committed the suicide was 5 males:1 femal...

While psychiatrists in the West are reaping the benefits of the surge in drug development during the past 10 years, psychiatrists in Japan are currently treating mental illness with a psychopharmacologic armamentarium that was considered state of the art in the United States in the early 1980s. None of the new generation antidepressants, antianxiety agents, or antipsychotics that have made grea...

As part of a WHO project on parasuicide, the medications used for self-poisoning in the Stockholm area were studied. The prescribing rates of the medications were estimated from an independent survey of prescriptions. Anxiolytics, hypnotics, and analgesics were the drugs most commonly used for parasuicide. Related to prescribing rates, antipsychotics and anxiolytics represented an increased ris...

Cannabidiol (CBD), a non-psychotomimetic compound of the Cannabis sativa, has been reported to have central therapeutic actions, such as antipsychotic and anxiolytic effects. We have recently reported that Spontaneously Hypertensive Rats (SHRs) present a deficit in social interaction that is ameliorated by atypical antipsychotics. In addition, SHRs present a hyperlocomotion that is reverted by ...