Mallory's (;alcoholic') hyaline has been found in hepatocytes in 18 of 70 patients with primary biliary cirrhosis. These inclusions have previously been noted in only three cases of primary biliary cirrhosis. Current views on the nature of Mallory's hyaline are briefly discussed.

Infantile systemic hyalinosis is a rare disorder characterized by widespread deposition of hyaline. They usually present with skin lesions, joint contractures, and intractable diarrhea. We report a 2 year 4 month old boy with growth retardation, typical facial appearance, gingival enlargement, generalized stiff skin, joint contractures, and intermittent diarrhea. Skin biopsy revealed depositio...

AIMS We retrospectively analyzed clinicopathologic features of 8 cases of hepatitis B virus-associated glomerulonephritis with hyaline thrombi, to confirm the diagnosis of cryoglobulinemic glomerulonephritis (CRYGN) associated with HBV infection. METHODS Retrospective analysis was carried out with demographic information, clinical manifestations, laboratory parameters, pathological and progno...

BACKGROUND Little is known about the relationship between splenic arteriolar hyaline and cause of death. The purpose of this retrospective study was to evaluate the clinicopathological significance of splenic arteriolar hyaline in autopsy cases and estimate the applicability of hyaline for diagnosing the cause and rapidity of death. METHODS Archival data and histological slides from 82 cases ...

THE problem of the splitting of the glomerular basement membrane originated with the observations of Jones (I953, I957) on the histogenesis of membranous thickening, made possible by means of a new method of staining (silver-methenamine). In his opinion this thickening was caused by the splitting of the basement membrane due to the deposition of a hyaline substance between the two layers. Jones...

In extra-capsular extraction of cataract in which the central portion of the anterior capsule is removed, or in injury of the lens, or in discission operations in which the anterior capsule is torn and the central portion of the lens substance is penetrated and becomes absorbed, a greater part of the capsule sac remains intact. According to Wessely (1910), when the central part of the anterior ...

INTRODUCTION It is common for leiomyoma to undergo various secondary changes like hyaline degeneration, cystic change, myxoid degeneration, infection, necrosis, calcification, red degeneration and very rarely ossification. They are said to result from inadequate blood supply resulting in replacement of muscle fibres by hyaline material, collagen, calcium, mucopolysaccharides or a combination of...

Renal hyaline droplet formation is described in two patients with haemoglobinuria. The droplets were shown to contain haemoglobin by a histochemical method. The findings are correlated with the results of recent experimental studies which have demonstrated that renal hyaline droplets are phagosomes containing absorbed protein and not products of cellular degeneration as was previously thought.