exposed to varicella, but her son became secondarily infected with varicella about 2 weeks after her illness started. She had the characteristic varicella rash, most of which had already scabbed. Her visual acuity was 20/20 in her right eye and 20/40 in her left. There was a left relative afferent pupillary defect. Funduscopy showed left optic disk edema with no visible retinal or choroidal les...

Purpose: To identify the clinical characteristics and predictors of visual outcomes in acute anterior optic neuritis patients treated with high-dose steroid pulse therapy using spectral domain optical coherence tomography (SD-OCT).Methods: In this study, medical records 34 intravenous followed-up for at least 3 months were retrospectively reviewed. The divided into two groups based on final bes...

Objective: To assess visual acuity and contrast sensitivity in various form of Optic neuritis patients. Study Design Settings: It was a hospital based cross sectional study conducted eye department Teaching hospital, University Lahore Pakistan. Total duration the 4 months from January 2022-April 2022. Methods: A total 32 patients were included study. Purposive sampling technique adopted for sam...

Optic neuritis is a clinical syndrome resulting from inflammation, demyelination, or infection of the optic nerve. Its diagnosis and treatment are complicated. In 1884, Nettleship first reported 28 cases of optic neuritis whose clinical symptoms have been accepted up to the present without any change. On the other hand, the development of diagnostic procedures and steroid therapy have also alte...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Fijałkowska-Cmokowicz G, Filipek E, Lenik M, Tronina A. Evaluation of the ganglion cell and inner plexiform layer in children with optic neuritis. Klinika Oczna / Acta Ophthalmologica Polonica. 2023. doi:10.5114/ko.2023.124699. APA Fijałkowska-Cmokowicz, G., Filipek, E., Lenik, M., & Tronina, (2023). https://doi.o...

Extensive optic nerve demyelinating lesions on magnetic resonance imaging (MRI) in adults could indicate a diagnosis other than multiple sclerosis with worse prognosis such as neuromyelitis optica. We report the frequency of longitudinally extensive lesions in children with first events of optic neuritis. Subjects had brain or orbit MRI within 3 months of onset and were evaluated at the Univers...

Longitudinal studies have shown that brain white matter lesions are strong predictors of the conversion of unilateral optic neuritis to multiple sclerosis (MS) in Caucasian populations. Consequently brain MRI criteria have been developed to improve the prediction of the development of clinically definite multiple sclerosis (CDMS). In Asian populations, optic neuritis may be the first sign of cl...

OBJECTIVE To determine if adenoviral-mediated transfer of the gene for catalase (CAT), the reactive oxygen species scavenger, suppresses experimental optic neuritis. CLINICAL RELEVANCE Gene therapy with CAT delivered by an adeno-associated viral vector was previously shown to suppress experimental optic neuritis. Because the transduction of protein expression with recombinant adeno-associated...

To the outpatient facility of the Department of Ophthalmology, Faculty Hospital Brno, Czech Republic, E.U., was in June 2013 referred a 24 years old man with the suspicion of Foster Kennedy syndrome. On the fundus examinations, the findings were in correlation with the symptoms of this syndrome: slightly pale optic disc of the right eye and edema with the anterior extension of the optic nerve h...