Background and Objective: Recent studies have shown that not only the quantity, but also the quality of dietary fatty acids can affect lipid parameters. Elaidic acid is a major hydrogenated by-product of vegetable oil play a role in the development of cardiovascular disease, especially atherosclerosis, through changing lipid profile and increase in inflammation and inflammatory factors. On the ...

Background: TNF-α and IL-6 are both pleiotropic cytokines playing major roles in cancer-associated cytokine networks. They have previously been investigated for their function in skin malignancies, mostly melanomas, and studies on NMSC patients are relatively fewer. In this study, we aimed to investigate the associations of serum levels of IL-6 and TNF-α with NMSCs and its clinicopathological f...

inflammatory bowel disease (ibd) is a chronic disease of unknown etiology, in which genetic factors, seem to play an important role in the disease predisposition and course. assessment of tumor necrosis factor (tnf-α) gene polymorphisms in many populations showed a possible association with ibd. considering the genetic variety in different ethnic groups, the aim of the present study was to inve...

conclusions special high-risk groups, including patients with ltbi, should be treated before receiving tnf-α inhibitors. the tuberculin skin test (tst) is a somewhat cost-effective test for the diagnosis of ltbi. however, its usefulness with respect to false results should be re-evaluated in this situation. results there were somewhat different approaches proposed by various researchers regardi...

introduction: helicobacter pylori (h. pylori), is a bacterium responsible for upper gastrointestinal tract diseases. the 16s rrna is a common h. pylori gene which are usually preferred for diagnosis purpose. the aim of this study was to determine the prevalence and abundance of 16s rrna in fecal samples and also evaluate correlation between the level of 16s rrna and activities of the cytokines,...

this study aimed at determining the chronic and acute effect of submaximal pedaling activity along with blood flow restriction on serum bdnf, tnf-α and bdnf/tnf-α ratio in active men. 24 physical education students at kharazmi university volunteered for the study. they were divided into three groups: pedaling with lower extremity vascular occlusion (n=8), pedaling without occlusion (n=8), and c...