The GnRH analogue has been shown to be effective in the treatment of
precocious puberty when given as a daily subcutaneous injection. We studied
the effectiveness of a long-acting GnRH analogue, Triptoreline, for the
treatment of central precocity, by suppressing gonadotropin and estradiol
secretion in three children with true precocious puberty. One month after
single dose intramuscular i...