نتایج جستجو برای: amphetamines
تعداد نتایج: 1006 فیلتر نتایج به سال:
Drug abuse robs individuals of their jobs, their families, and their free will as they succumb to addiction; but may cost even more: a life of disability or even life lost due to stroke. Many illicit drugs have been linked to major cardiovascular events and other comorbidities, including cocaine, amphetamines, ecstasy, heroin, phencyclidine, lysergic acid diethylamide, and marijuana. This revie...
BACKGROUND Cardiovascular or cerebrovascular events associated with drug abuse have been frequently reported, particularly in young patients. The drugs include generally cocaine, heroin, and amphetamines. Although marijuana is among the widely used narcotics in the world, stroke associated with the marijuana use is infrequently reported. METHODS Stroke caused by the use of marijuana was inves...
This study compares adults with and without attention deficit hyperactivity disorder (ADHD) on measures of direct and displaced aggression and illicit drug use. Three hundred ninety-six adults were administered the Wender Utah Rating Scale, the Risk Behavior Assessment, the Aggression Questionnaire (AQ), and the Displaced Aggression Questionnaire (DAQ). Those with ADHD were higher on all scales...
Amphetamine use in the 1950s, 1960s and 1970s resulted in many reports of death attributed to toxicity. Few approved indications exist for the medical use of amphetamine and its derivatives. Unfortunately, when compared with other illegal street drugs, nonmedical uses of various amphetamines have been increasing in the 1990s. The abuse of amphetamines continues to cause severe and lethal intoxi...
Amphetamines elevate extracellular dopamine, but the underlying mechanisms remain uncertain. Here we show in rodents that acute pharmacological inhibition of the vesicular monoamine transporter (VMAT) blocks amphetamine-induced locomotion and self-administration without impacting cocaine-induced behaviours. To study VMAT's role in mediating amphetamine action in dopamine neurons, we have used n...
Amphetamine withdrawal can induce a condition with the symptoms of major depression. We report the case of a 46-year-old woman with antecedents of abuse of amphetamines and amphetamine derivatives from age 16 to age 41, who in the 5 years since withdrawal presented recurrent depression resistant to treatment. She was treated with maximum doses of selective serotonin reuptake inhibitors and lith...
In monoaminergic neurons, the vesicular transporters and the plasma membrane transporters operate in a relay. Amphetamine and its congeners target this relay to elicit their actions: most amphetamines are substrates, which pervert the relay to elicit efflux of monoamines into the synaptic cleft. However, some amphetamines act as transporter inhibitors. Both compound classes elicit profound psyc...
The focus of this investigation was the relationship between anxiety disorders and lifetime use of amphetamines, cocaine, hallucinogens and heroin in two contemporaneous samples. Data from two independent community surveys conducted in the US (N=5877) and Ontario (N=8116) were used to assess whether a lifetime anxiety disorder diagnosis (social phobia, panic disorder, agoraphobia, specific phob...
4.1 Screening Strategy.................................................................................................................68 4.2 General Concepts ..................................................................................................................68 4.3 Basic Strategies .......................................................................................................
Objective: Meth-amphetamines are a group of amphetamines that are highly absorbent and effective. The aim of this study was to evaluate the efficacy of well-being therapy in the dimensions of addiction severity index in active methamphetamine users. Method: In a randomized clinical trial in the form of a single site study, from March to June 2016, the number of 30 consumers was selected volunta...
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