Journal:
:acta medica iranica
0
fatemeh behmanesh department of pediatrics, ghaem hospital, mashhad university of medical science, mashhad, iran.
reza amin department of immunology and allergy, shiraz university of medical science, shiraz, iran.
mohammad khajedaluee department of community medicine and health, mashhad university of medical science, mashhad, iran.
marvin j fritzler department of biochemistry and molecular biology, school of medicine, university of calgary, canada.
systemic sclerosis is a generalized disorder of connective tissue clinically characterized by thickening and fibrosis of the skin and by distinctive forms of involvement of internal organs. one of the hallmarks of systemic sclerosis is the presence of serum autoantibodies against a variety of nuclear and cytoplasmic antigens. the primary purpose of this study was to identify the autoantibodies ...