Obesity and the metabolic syndrome are closely related and have become increasingly prevalent in Korea. The cardiovascular disease (CVD) risk factors comprising the metabolic syndrome have previously been associated with increased hypothalamic-pituitary-adrenal axis (HPAA) activity, but the associations have not been extensively examined in non-Caucasian populations. The aim of the present stud...

background: acute intoxication with alp is extremely lethal. the present study was conducted to determine the range of serum cortisol levels in alp poisoning and its correlation with patient outcome. methods: this study was carried out on patients who were intoxicated with alp. their demographic data and pertinent findings in their history and physical examination were recorded at the time of a...

Cortisol is secreted by the central hypothalamo-pituitary-adrenal axis and affects many target organs and tissues, particularly in response to stressor demands and infection. Recent data reporting cortisol synthesis in hair follicles have shown the existence of a parallel "peripheral" HPA-axis. However, although there is evidence from in vitro studies and single-observation comparisons between ...

The link between obesity and increased risk of mortality is well established. However, those who are obese have greater survival when they have chronic diseases such as rheumatoid arthritis or cardiac failure; this is known as the ‘‘obesity paradox’’. The obesity paradox is most probably attributable to obese individuals being more susceptible to milder forms of disease than normal-weight indiv...

BACKGROUND Binge eating episodes characterized by loss of control are hypothesized to be accompanied by changes in hypothalamic pituitary adrenal (HPA) axis functioning. Cortisol is an end product of this neuroendocrine stress system. PURPOSE The aim of this study was to examine the cortisol levels and the awakening cortisol response (ACR) in obese persons showing binge eating after surgery f...

Obstructive sleep apnoea (OSA), common in children with obesity, is associated with cardiovascular morbidity. Autonomic dysfunction has been suggested to be a key player in the development of these complications. We investigated the relationship between obesity, OSA and sympathetic activity in children. 191 children with obesity were included and distributed into two groups: 131 controls and 60...