نتایج جستجو برای: alpha 1 1 antitrypsin

تعداد نتایج: 2882244  

Journal: :Journal of clinical pathology 1984
M Legge G B Duff H C Potter M M Hoetjes

Maternal serum alpha 1-antitrypsin concentrations were measured serially in pregnant women who were normotensive and those with mild, moderate, and severe hypertension of pregnancy from 27 weeks' gestation to term. alpha 1-antitrypsin concentrations increased with advancing gestation in all four groups. In addition, the hypertensive pregnancies showed higher than normal concentrations at each s...

Journal: :The Journal of clinical investigation 1981
J E Gadek G A Fells R L Zimmerman S I Rennard R G Crystal

The current concepts of the pathogenesis of emphysema hold that progressive, chronic destruction of the alveolar structures occurs because there was in imbalance between the proteases and antiproteases in the lower respiratory tract. In this context, proteases, particularly neutrophil elastase, work unimpeded to destroy the alveolar structures. This concept has evolved from consideration of pat...

2014
Violette Frochaux Diana Hildebrand Anja Talke Michael W. Linscheid Hartmut Schlüter Mark Isalan

The human serine protease high temperature requirement A1 (HTRA1) is highly expressed in the placental tissue, especially in the last trimester of gestation. This suggests that HTRA1 is involved in placental formation and function. With the aim of a better understanding of the role of HTRA1 in the placenta, candidate substrates were screened in a placenta protein extract using a gel-based mass ...

Journal: :Annals of Pediatric Endocrinology & Metabolism 2018

Journal: :Annals of the American Thoracic Society 2016

Journal: :Journal of Allergy and Clinical Immunology 2020

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