Benign prostatic hyperplasia (BPH)-associated lower urinary tract symptoms (LUTS) are highly prevalent in older men. Medical therapy is the first-line treatment for LUTS due to BPH. Alpha-adrenergic receptor blockers remain one of the mainstays in the treatment of male LUTS and clinical BPH. They exhibit early onset of efficacy with regard to both symptoms and flow rate improvement, and this is...

Tumor necrosis factor alpha (TNF-α) a cytokine has been shown to be the key player during the pathogenesis of several autoimmune inflammatory disorders (presumably sterile inflammation) including rheumatoid arthritis (RA). Several studies have shown that TNF-α is mainly involved in the proinflammatory responses. However recent studies have reported multifunctional role of TNF-α during the devel...

We investigate the use of alternative divergences to Kullback-Leibler (KL) in variational inference(VI), based on the Variational Dropout [10]. Stochastic gradient variational Bayes (SGVB) [9] is a general framework for estimating the evidence lower bound (ELBO) in Variational Bayes. In this work, we extend the SGVB estimator with using Alpha-Divergences, which are alternative to divergences to...

Heavier p isotopes are believed to be produced through the γ-process. The path of γ-process can modelled with network calculations. These calculations include about 20000 reactions on more than 2000, mostly unstable nuclei, many these involves alpha particles. Theoretical cross sections involving particles found very sensitive alpha-nucleus optical potential, which is not known well enough at l...

BACKGROUND AND AIM: Recurrent aphthous stomatitis (RAS) is a lesion of the oral cavity with an unknown etiology. Several studies have been performed on the role of tumor necrosis factor-alpha (TNF-α) in RAS. The main purpose of this paper was to review TNF-α level and its gene polymorphism in patients with RAS, the factors influencing the production of TNF-α, a...

Alpha (α)-E-catenin is a component of the cadherin complex, and has long been thought to provide a link between cell surface cadherins and the actin skeleton. More recently, it has also been implicated in mechano-sensing, and in the control of tissue size. Here we use the early Xenopus embryos to explore functional differences between two α-catenin family members, α-E- and α-N-catenin, and thei...

We developed an immunochromatography-based assay for detecting antibodies against recombinant α-galactosidase A proteins in serum. The evaluation of 29 serum samples from Fabry patients, who had received enzyme replacement therapy with agalsidase alpha and/or agalsidase beta, was performed by means of this assay method, and the results clearly revealed that the patients exhibited the same level...

Abstract A regular rotating MOG (modified gravity) compact object is derived that reduces to the Kerr black hole when parameter $$\alpha =0$$ α = 0 . Physical consequences of dark object, which everywhere in spacetime for > \alpha _\mathrm{crit}=0.67...

Objective: The goal of this research was to determine the influence of 4 weeks aerobic training on gene expression of tumor necrosis factor alpha (TNF-α), hypoxia-inducible factor-1 alpha (HIF-1α) and vascular endothelial growth factor (VEGF) in the cardiac tissue of diabetic rats. Materials and Methods: In an experimental study, 30 male wistar rats were partitioned into three groups (n=10), d...

For the iteration of spherical average (A1)N and Laplace operator Δ, we consider boundedness Δ(A1)N on α-modulation spaces \(M_{p,q}^{s,\alpha }\). The authors obtain some sufficient necessary conditions to ensure spaces. main theorems significantly improve known results.