AIMS To consider a possible genetic origin for the persistent unexplained increase in plasma alkaline phosphatase (ALP) in five non-related patients referred over an 18 month period. METHODS Plasma ALP isoenzyme activities were measured in patients and their first degree relatives. RESULTS In each patient there was a noticeable increase in intestinal plasma ALP, either alone or accompanied ...

We have studied five patients who have exhibited an unusual alkaline phosphatase isoenzyme (ALP EC 3.1.3.1) migrating in an ultrafast position electrophoretically on cellulose acetate. This ALP isoenzyme has been identified in patients with benign and malignant liver diseases. In addition, a number of these patients exhibited a regular ALP liver isoenzyme and a fast (preliver) ALP isoenzyme in ...

Alkaline phosphatises (ALP) are a group of isoenzymes produced by liver (isoenzymes ALP1-1), bones (isoenzymes ALP2), kidneys, small intestine and placenta (isoenzymes ALP-3) [1,2]. The serum ALP level represents the total amounts of isoenzymes that are released from the tissues into the bloodstream. Placenta ALP is physiologically produced by placenta at the brush border membranes of the syncy...

In this paper, we report, for the first time, that by modulating pump beam to suppress ASE effect we realized ultra-low repetition rate output in an all fiber based Er:Yb codoped master oscillator power amplifiers (MOPA) system. Combined with pulse shaping technology, pulses with up to 205 µJ pulse energy and 200 ns pulse duration were obtained at Hz level.

BACKGROUND/AIMS Serum alkaline phosphatase (ALP) levels tend to increase after hepatectomy, however, no previous examinations have yet focused on the relationship between liver regeneration and the individual ALP isoenzymes levels. METHODOLOGY Forty living liver transplantation donors who underwent hemi-hepatectomy were herein investigated. We evaluated the serum ALP levels and ALP isoenzyme ...

We report the performance characteristics of an assay for determination of bone alkaline phosphatase (ALP) activity after immunoadsorption in microplate wells. Between-run imprecision was between 7.1% and 11.2%. The detection limit was 1.0 U/L. Comparisons with an immunoradiometric test for determination of bone ALP mass concentrations yielded the following regression equation: y = 3.11 + 1.33x...