Phosphatidylinositol 3-kinase (PI3-K) amplification and phosphatase and tensin homolog (PTEN) deletion-caused Akt activation contribute to the development of prostate cancer. Mammalian target of rapamycin complex 2 (mTORC2) is a kinase complex comprised of mTOR, Rictor, mSin1, mLST8/GβL and PRR5 and functions in the phosphorylation of Akt at Ser473. Herein, we report that mTORC2 plays an import...

This study evaluated the acute inflammatory response induced by carrageenin in the swim bladder of Nile tilapia supplemented with the mixture of natural extracts of propolis and Aloe barbadensis (1:1) at a concentration of 0.5%, 1% and 2% in diet during 15 days. Thirty-six fish were distributed into four treatments with three replicates: fish supplemented with 0.5% of admix of extracts of propo...

234 Abstract— The growth and health status of plants can be accessed from the electrical properties of its limbs such as leaves and stem. Present investigations were carried out to study the electrical impedance of Aloe Barbadensis Miller (Aloe-vera) leaves for investigating the effect of external ac current on its tissues Impedance was estimated over the frequency ranging from 500 Hz to 20 kHz...

Ingredients in Aloe Vera Gel Mannose and glucose are the most significant sugars found in the Aloe vera gel, and they can be used to assay the activity of Aloe vera. The gel contains important sterols which can have anti-inflammatory activity. Amino acids such as tryptophane and phenylaianine reduce inflammation. Studies have shown that vitamin C & B complex can maintain adrenalectomized animal...

The effects of the exudate of Aloe barbadensis leaves on oxidative stress and some antioxidant status of streptozotocin induced diabetic rats were studied. There was significant reduction in scavenging enzymes like superoxide dismutase (SOD) activity and significant increase in signs of oxidative tissue damage, such as lipid peroxidation products (plasma MDA) in streptozotocin induced diabetic ...

The possibility of natural cancer therapy has been recently suggested by advances in the knowledge of tumor immunobiology. Either cytokines such as IL-2, or neurohormones, such as the pineal indole melatonin (MLT), may activate anticancer immunity. In addition, immunomodulating substances have also been isolated from plants, particularly from Aloe vera. Preliminary clinical studies had already ...

Freeze-dried juice obtained from Aloe vera and heated for 15 minutes at 80 degrees inhibited several test microorganisms. Species of Aloe have had a long history as drug plants. This was pointed out by Morton (1) in a recent comprehensive review of Aloe from the standpoint of folk use and commercial exploitation. Fly and Kiem (2) recently carried out an investigation to ascertain whether Aloe v...

Instantly recognizable by its spiky green leaves, aloe vera is a succulent plant that stores water in its fleshy leaves and thus thrives in arid climates like deserts. Its use as a medicinal plant for soothing various external and internal woes dates back thousands of years. Currently, there?s some evidence to support its use for many of the ailments it?s traditionally been used to treat. Both ...

Traditional herbal drugs have a great demand in under developed countries due to their efficacy, low cost and lesser adverse effects, and they are considered to be “natural. Aloe vera at the dose of 500 mg body weight per oral was studied for the gross toxicities and hepatoprotective effect and observed the level of liver biochemical parameters in rabbits. Aloe vera showed highly significant (p...

Anthraquinones are natural phenolic compounds, which are reported to act as anti-aging, anti-inflammatory, antioxidant, anti-cancer, laxative and antitumor agents. They are abudant in plants like candle bush, aloes, cascara bark and rhubarb. The present work was to observe the effect of different forced degradation conditions by high-performance thin layer chromatography on potential markers i....