INTRODUCTION: Allograft reconstruction after resection of primary bone sarcomas has a non-union rate of approximately 20%. Achieving a wide surface area of contact between host and allograft bone is one of the most important factors to help reduce the non-union rate. We developed a novel technique of haptic robot-assisted surgery to reconstruct bone defects left after primary bone sarcoma resec...

The goal of this study was to determine how well a medial meniscal allograft restores the normal contact mechanics of the medial tibial plateau at the time of implantation. We measured maximum pressure, mean pressure, and contact area of the intact human cadaveric knee, the knee after meniscectomy, the knee with the original meniscus removed and reimplanted as an autograft, and the knee with an...

INTRODUCTION: Disc Degenerative Disease (DDD) is one of the most common causes of low back pain (LBP), to date; there is no one effective treatment of DDD. Artifical disc implantation have been proposed as a motion preservation solution to DDD. However, studies of artificial disc implants have suggested that the artificial discs causes permanent changes in the kinematics of the spine and cannot...

Long-term kidney allograft survival continues to remain an elusive goal. Kidney transplant recipients are believed to be at high risk for loss of allograft function, and new, potentially non-nephrotoxic immunosuppressive medications are advocated to improve long-term allograft survival. To evaluate the efficacy of such therapeutic interventions, information regarding the change in GFR among kid...

Vascular endothelial cells act as antigen-presenting cells in the lung allograft and stimulate alloreactive host lymphocytes. Activated lymphocytes and cytokines can induce expression of leukocyte-endothelial adhesion molecules that facilitate invasion of the allograft by circulating leukocytes. To define the role of endothelial HLA class II antigen and adhesion molecule expression in lung allo...

Objective: To assess the effect of low-level laser therapy (LLLT) on morselized bone allograft incorporation. Material and Methods: Four rabbits were used as bone tissue donors. Morselized bone allografts and autografts were placed into the calvaria of 20 rabbits divided across four groups: two LLLT groups (allograft, autograft and blood clot) and two non-irradiated control groups (allograft, a...

PURPOSE To compare the incidence of bacterial infection in anterior cruciate ligament (ACL) reconstruction with autograft versus allograft. METHODS We completed a retrospective medical record review of ACL reconstructions performed at our institutions between 2001 and 2005. These included 170 autograft, 628 allograft, and 3 combined autograft/allograft reconstructions. Data collection include...

Objective: The present study aimed to assess ridge augmentation with an allograft bone ring versus GBR titanium