The aim of this study was to clinically evaluate the use of alloderm to increase the width of attached gingiva. Nine patients were selected. The inclusion criteria were: attached gingiva smaller than 1 mm; Miller's class I and II gingival recession; patients able to attend control dental appointments; absence of periodontal pocket and endodontic treatment in the neighboring area where the acell...

BACKGROUND To minimize the inflammatory reaction and improve healing, a new modified dermal substitute composed of an atelocollagen, chondroitin-6-sulfate, and amniotic membrane (AM) was applied to full-thickness skin defects in a pig. Atelocollagen was extracted from bovine skin, and two modified dermal substitutes were generated according to the cross-linking type. METHODS The AM-collagen d...

RESULTS: All patients had a positive Grind test preoperatively and a negative test after 6 months. Statistically significant improvements were seen (Means scores with P values) VAS at rest 3.25 to 1.425 (P=0.0138), VAS on activity 7.7 to 3.9 (P=0.0021), ROM 46 to 53 (P= 0.0095) and DASH 47.23 to 18.7 (P=0.0046). Strength and Kapandji score improved insignificantly at 6 months. There were no sig...

We fabricated ex vivo produced oral mucosa equivalent (EVPOME) from patients' oral mucosal keratinocytes without using animal-derived serum or feeder layer cells. To confirm the clinical benefits of 1) early initiation of epithelialization, 2) a short period until complete healing and 3) negligible scar contracture, the mechanism of wound healing after EVPOME transplantation for oral mucosal de...