Hemophagocytic Lymphohistiocytosis (HLH) is a devastating disorder of uncontrolled immune activation characterized by clinical and laboratory evidence of extreme inflammation. This syndrome can be caused by genetic mutations affecting cytotoxic function (familial HLH) or secondary to infectious, rheumatologic, malignant, or metabolic conditions (acquired HLH). Prompt recognition is paramount an...

T he nematode worm, C. elegans, sheds its exoskeleton at particular life stages, and Alison Frand believes that understanding this molting process might provide new insights into diseases affecting humans. Some of the potential medical benefi ts lie in the similarities between the worms' exoskeleton and our own skin and connective tissues, while other benefits might lie in the unique aspects of...

Raymond A. Harvey, MPH; Jeremy Rassen, ScD; Carly Kabelac, BS; Wendy Turenne, MS; Sandy Leonard, Reyna Klesh, William Meyer III, PhD, D(ABMM), MLS(ASCP)CM; Harvey W. Kaufman, MD, MBA; Steve Anderson, PhD; Oren Cohen, MD; Valentina I. Petkov, Kathy Cronin, Alison L. Van Dyke, Douglas R. Lowy, Norman E. Sharpless, Lynne T. Penberthy, MPH

Yoram Rubin, Department of Civil and Environmental Engineering, University of California at Berkeley, 435 Davis Hall, Berkeley, CA 94720. ([email protected], [email protected]) Alberto Bellin, Dipartimento di Ingegneria Civile ed Ambientale, Università di Trento, via Mesiano 77, I-38050 Trento (Italy). ([email protected]) and Alison E. Lawrence and , Department of Civil and...

1 2 3 4 Constitutively Opa-expressing and Opa-deficient Neisseria gonorrhoeae differentially 5 stimulate and survive exposure to human neutrophils 6 7 Louise M. Ball and Alison K. Criss 8 9 Department of Microbiology, Immunology, and Cancer Biology, 10 University of Virginia Health Sciences Center, Charlottesville, Virginia, USA 11 12 Running title: Gonococcal opa-mediated interactions with neu...

Andreas A. Werdich, Franz Baudenbacher, Igor Dzhura, Loice H. Jeyakumar, Prince J. Kannankeril, Sidney Fleischer, Alison LeGrone, Dejan Milatovic, Michael Aschner, Arnold W. Strauss, Mark E. Anderson, and Vernat J. Exil Division of Cardiology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville; Division of Gastroenterology, Vanderbilt University Medical Center, Nashvi...

Holly E. Barker, Joan Chang, Thomas R. Cox, Georgina Lang, Demelza Bird, Monica Nicolau, Holly R. Evans, Alison Gartland, and Janine T. Erler# Section of Cell and Molecular Biology, Cancer Research UK Tumour Cell Signalling Unit, The Institute of Cancer Research, London SW3 6JB, UK; Department of Mathematics, Stanford University, Stanford CA 94305, USA; The Mellanby Centre For Bone Research, De...