microRNAs function in diverse developmental and physiological processes by regulating target gene expression at the post-transcriptional level. ALG-1 is one of two Caenorhabditis elegans Argonautes (ALG-1 and ALG-2) that together are essential for microRNA biogenesis and function. Here, we report the identification of novel antimorphic (anti) alleles of ALG-1 as suppressors of lin-28(lf) precoc...

Multifunctional hydrogels are a class of materials offering new opportunities for interfacing living organisms with machines due to their mechanical compliance, biocompatibility, and capacity be triggered by external stimuli. Here, we report dual magnetic- electric-stimuli-responsive hydrogel the disassembled reassembled up three times through reversible cross-links. This allows its use as an e...

In this study, polyacrylamide/alginate (PAAm/Alg) based hydrogels have been synthesized and investigated. The four different produced contained concentrations of single- or double- network polymer: 15 wt.% single-network (SN-15), 30 (SN-30), double-network (DN-15), (DN-30). tribological performance these was investigated by using a custom pin-on-disc tribometer in phosphate buffered saline (PBS...

In this study, sodium alginate film (Alg) was coated with electrospun collagen glue (Col) extracted from rabbit skin waste, loaded different commercial antimicrobial agents (chitosan, AG425K and ZnONPs) investigated in terms of morphological, structural biological properties. The nanostructures were characterized using scanning electron microscopy coupled the energy-dispersive X-ray (SEM/EDS), ...

‎Let $mathscr{L}$ be a commutative subspace lattice generated by finite many commuting independent nests on a complex separable Hilbert space $mathbf{H}$ with ${rm dim}hspace{2pt}mathbf{H}geq 3$‎, ‎${rm Alg}mathscr{L}$‎ ‎the CSL algebra associated with $mathscr{L}$ and $mathscr{M}$ be an algebra containing ${rm Alg}mathscr{L}$‎. ‎This article is aimed at describing the form of‎ ‎additive mapppi...

The present study aimed to investigate the adsorption capacity of two anionic dyes, namely, Congored (CR) and Coralene Dark Red2B (DR), onto prepared alginate (Alg) chitosan(Cs) biopolymer films. biopolymers were combined at different mass ratios using a “solvent-cast” process incorporate their unique properties evaluate effectiveness in removing dyes. All samples characterized by means Fourier...

Porous alginate (Alg) hydrogels possess many advantages as cell carriers. However, current pore generation methods require either complex or harsh fabrication processes, toxic components, extra purification steps, limiting the feasibility and affecting cellular survival function. In this study, a simple cell-friendly approach to generate highly porous cell-laden Alg based on two-phase aqueous e...

MicroRNAs are regulators of gene expression whose functions are critical for normal development and physiology. We have previously characterized mutations in a Caenorhabditis elegans microRNA-specific Argonaute ALG-1 (Argonaute-like gene) that are antimorphic [alg-1(anti)]. alg-1(anti) mutants have dramatically stronger microRNA-related phenotypes than animals with a complete loss of ALG-1. ALG...

The apoptosis-linked gene ALG-2 encodes a Ca(2+)-binding protein of the penta EF-hand family. To investigate the Ca(2+) binding properties of the recombinant ALG-2 protein, we have cloned ALG-2 cDNA from mouse liver mRNA. Sequence analysis showed that two types of clones were present. One (named ALG-2,5) corresponds to the published ALG-2 sequence (Vito, P., Lacana, E., and D'Adamio, L. (1996) ...