1. A vitamin &-deficient diet was fed to an adult male subject to confirm previously described changes in tryptophan metabolism and urinary 4-pyridoxic acid excretion, and erythrocyte alanine and aspartate aminotransferase activities. 2. The results were compared with those obtained in women taking oestrogencontaining oral contraceptives. 3. The development of dietary vitamin B, deficiency was ...

Recent studies have established a relation between elevated alanine aminotransferase levels in donor blood and the incidence of non-A, non-B hepatitis in recipients of such blood. Routine testing of donor blood for alanine aminotransferase activity in order to reduce hepatitis is not currently supported, largely because the results of such testing are unknown. We assessed the potential economic...

Involution of the thymus was observed in rats bearing AH 130 (solid-type) tumors. The thymus weight decreased with tumor growth. Daily injection of a pharmacological dose of hydrocortisone into normal rats resulted in involution of the thymus and marked increase in alanine aminotransferase activity. This treatment also caused slight increase in the activity of tyrosine aminotransferase but not ...

OBJECTIVE This study sought to determine the serum aminotransferase levels of patients with predialysis chronic kidney disease and establish their relationships with serum creatinine levels and glomerular filtration rate. METHODS Patients with chronic kidney disease were evaluated between September 2011 and May 2012. Aminotransferase and creatinine serum levels were measured using an automate...

Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis-supplemented diet. Biochemical and hematological parameters investigated included serum protein, total cholesterol, lipid peroxidation, haemoglobin, white blood cells, Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Glutathione...

Increased aminotransferases often indicate hepatic injury but are also increased with damage to heart and muscle (1 ). Testing for creatine kinase is helpful, especially when the ratio of aspartate aminotransferase to alanine aminotransferase is 3:1, a value uncommon with liver injury. In acute liver injury the aspartate aminotransferase/alanine aminotransferase ratio is usually 2:1. When measu...

We evaluated the Kodak Ektachem DT60/DTSC and the Boehringer Mannheim Reflotron for measuring activity concentrations of six enzymes. The Ektachem CVs for low concentrations of aspartate aminotransferase and alanine aminotransferase were high. As compared with the Ektachem and a routine "wet-chemistry" system, values for aspartate aminotransferase and alanine aminotransferase were lower as meas...