Ascorbic acid (vitamin C) prevented diphtheria toxin from inhibiting the incorporation of [U-14C]-alanine into trichloroacetic acid precipitable material in HeLa cells. Ascorbic acid did not exhibit an effect on the adenosine diphosphate-ribosylation of amino acyl transferase II nor did it separate fragment A from fragment B in "nicked" toxin. A non-specific reducing agent, para-methylaminophen...

We examine a logical foundation for the intersection and union types assignment system (IUT). The proposed system is Intersection and Union Logic (IUL), an extension of Intersection Logic (IL) with the canonical rules for union. We investigate two different formalisms for IUL, as well as its properties and its relation with minimal intuitionistic logic.

OBJECTIVE Comparison of gamma glutamyltransferase in normal and type 2 diabetics. METHODS In a cross-sectional study, 100 apparently normal healthy subjects and, 47 type 2 diabetic subjects were selected from either sex with ages between 18-65 years. Subjects were measured for waist/hip ratio, BMI and serum levels of ALT, AST, Alk phosphatase and glutamyl transferase (GGT). The study excluded...

Apigenin, a dietary flavonoid, is reported to have several therapeutic effects in different diseases including cancer. Toxicity of Apigenin is however, least explored, and reports are scanty in literature. This warrants dose-specific evaluation of toxicity in vivo. In the present study, Apigenin was administered intraperitoneally to Swiss mice at doses of 25, 50, 100 and 200 mg/kg. Serum levels...

N,N-Dimethylformamide (DMF), an industrial solvent widely used throughout the world is a known toxic compound. Here, we studied the effects of acute exposure of DMF on liver and kidney in rats. Rats were treated intraperitoneally with a single dose of DMF (1.5 g/kg) for 24 and 48 h. Hepatic and nephrotoxicity was confirmed based on the significant increase in the serum levels of aspartate amino...

Gamma-glutamyltransferase activity in serum is shown to be competitively inhibited by the two substrates gamma-glutamyl-4-nitroanilide and glycylglycine. Awareness of this is of importance when one is choosing final reaction conditions for the assay of the enzyme. Gamma-glutamyltransferase probably acts by a "ping-pong bi-bi" kinetic mechanism, which fits with the double competitive substrate i...

Tyrosine aminotransferase purified from epimastigotes of Trypanosoma cruzi displays an additional activity of alanine aminotransferase, absent in all other tyrosine aminotransferases characterized so far. Since the parasite's genome contains a high number of copies of the tyrosine aminotransferase gene, we could not rule out the possibility that two very similar proteins, with changed specifici...

In 100 consecutive children aged below 18 years with confirmed typhoid fever, 29 had moderate hepatitis. Serum alanine amino transferase: lactate dehydrogenase (ALT: LDH) ratios of these 29 children at the time of hospitalization were compared with that of 29 children with acute viral hepatitis. The serum ALT: LDH ratio levels (expressed in multiples of upper limit of normal) was found to be le...

The present study was conducted to determine the hematobiochemical analysis of ostrich (Struthio camelus) with respect gender and progressive age. A total 40 apparently healthy ostriches both genders two age groups; young one (1 year 2.4 years: group A); adult (2.5 years 5 B) in equal number were used this study. Blood samples collected from wing vein maintained farms near Gogra Pakistan. For h...

OBJECTIVE: To investigate the serum antioxidant capacity and status of liver function parameters in Hepatitis B virus (HBV) C Virus (HCV) infected patients. METHODS: In this case-control study, fifty patients with HBV (28 male & 22 females), HCV females) age gender matched healthy controls were enrolled from May to August 2016. The was determined by measuring trolox equivalent oxidant (TEAC...