Objective: To evaluate the prevalence of reduced visual acuity (VA), refractive errors (RE), contrast sensitivity and strabismus in developmentally delayed (DD) patients.
 Methods: This descriptive cross sectional study was carried out Ophthalmology Departments Mayo Hospital, Lahore, The Children’s Lahore Multan from June 2019 to December 2019. We recruited 257 patients either gender, betw...

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Komisi Fatwa Majelis Ulama Indonesia telah mengeluarkan fatwa Nomor no 31 tahun 2020 Teantang Penyelenggaraan Shalat Jumat dan Jamaah Untuk mencegah Penularan Wabah Covid 19. Secara umum MUI sudah menyusun Pedoman Penetapan Nomor: U596/MUI/X/1997. Dalam pedoman tersebut disebutkan bahwa setiap harus berupa pendapat hukum yang mempunyai dasar-dasar paling kuat membawa maslahat bagi umat. Dasar d...

Background Cyclophosphamide (CYC) is currently used to induce remission in patients with ANCA-associated vasculitis (AAV). Once induction successful Azathioprine (AZA) given as maintenance (1). Concerns surround the use of cyclophosphamide which has an undesirable safety profile, limiting its patients. AZA shown be effective at maintenance, however rates relapse on are high. Rituximab (RTX) a b...

TOPIC: Pulmonary Manifestations of Systemic Disease TYPE: Medical Student/Resident Case Reports INTRODUCTION: A chylothorax is defined by the presence chyle within pleural cavity. Chylothoraces can be observed as a complication malignancy; however, Waldenstrom Macroglobulinemia (WM) has rarely been described potential cause. We present case refractory secondary to WM presenting periaortic mass,...

Background Dual energy x-ray absorptiometry (DEXA) has an established place in the diagnosis of osteoporosis and fracture risk estimation using FRAX® tool. DEXA is also useful producing morphometry data on bones including vertebrae at low radiation doses during appointments. Currently there exists limited clinical use for vertebral height measurement, with no published as a measurement. FRAX cu...

Phage Mu transposes promiscuously, employing MuB protein for target capture. MuB forms stable filaments on A/T-rich DNA, and a correlation between preferred MuB binding and Mu integration has been observed. We have investigated the relationship between MuB-binding and Mu insertion into ‘hot’ and ‘cold’ Mu targets within the E. coli genome. Although higher binding of MuB to select hot versus col...

Dear Editor, Ataxia with oculomotor apraxia type 1 (AOA1, MIM 208920) is an autosomal recessive disorder characterized by early-onset cerebellar ataxia, polyneuropathy, oculomotor apraxia, hypoalbuminemia, and hypercholesterolemia.1 It is caused by pathogenic variants of APTX, which encodes the aprataxin protein that is involved in DNA strand-break repair.1 We recruited a consanguineous family ...

Background: Patients with Systemic Lupus Erythematosus (SLE) are at risk of osteoporosis (OP) and fragility fractures (FFx) because the disease or its treatments. We assessed prevalence factors for OP in patients SLE. Objectives: Our objective is to determine bone mineral density (BMD) loss fracture SLE undergoing dual-energy X-ray absorptiometry (DXA). Methods: This a cross sectional study con...