There have been efforts to overcome the problem in treatment of cancer using medicinal plants. It has been shown that Citrus essential oil of contains different terpens with antitumor activities. In this study we sought to determine the cytotoxicity of essential oils of Iranian Citrus limon (L.), C. medica (L.), C. sinsensis (L.) peels on cancer cell lines. Essential oils were prepared by hydr...

The genus Carex belongs to tribe Cariceae, subfamily Caricoideae and family Cyperaceae. This genus, with about 2000 species in the world and more than 50 species in Iran, is the largest genus among the family. In expedition to North West and West of Iran, two species, namely, Carex acuta and C. cilicica as new records and C. flava, C. rostrata and C. supina as reinvestigated species are reporte...

Abstract. In this paper, we define the notion of C*-affine maps in the unital *-rings and we investigate the C*-extreme points of the graph and epigraph of such maps. We show that for a C*-convex map f on a unital *-ring R satisfying the positive square root axiom with an additional condition, the graph of f is a C*-face of the epigraph of f. Moreover, we prove som...

Tenofovir (TFV), an acyclic nucleoside phosphonate analogue of 2′deoxyadenosine, remains a first-line choice for the treatment of HIV infections under its prodrug form (i.e. tenofovir disoproxil fumarate, TDF). During the last decade, the use of TFV in pre-exposure prophylaxis (PrP) was first investigated as a vaginal microbicide gel (Mayer et al., 2006). More recently, rectal microbicide prepa...

OBJECTIVES We hypothesized that left ventricular (LV) remodeling and matrix loss in volume overload (VO) are mediated by bradykinin (BK) and exacerbated by chronic angiotensin-converting enzyme (ACE) inhibition. BACKGROUND Chronic ACE inhibition increases anti-fibrotic BK and does not attenuate LV remodeling in pure VO. The relative contribution of changes in extracellular matrix versus cardi...

Let Aut(X, B) be the group of all Borel automorphisms of a standard Borel space (X, B). We study topological properties of Aut(X, B) with respect to the uniform and weak topologies, τ and p, defined in [BDK1]. It is proved that the class of smooth automorphisms is dense in (Aut(X, B), p). Let Ctbl(X) denote the group of Borel automorphisms with countable support. It is shown that the topologica...

AMP deaminase activity (AMP->IMP+NH3) is the entry reaction to the purine nucleotide cycle. In skeletal muscle, excessive energy demands during contractions leads to a net production of ADP, because ATP hydrolysis exceeds ADP rephosphorylation. Elevations in ADP increase AMP, via the myokinase reaction. This accumulation of ATP hydrolysis products should lead to a catastrophic reduction in the ...