In gastrointestinal tissues, cumulative evidence from both in vivo and in vitro studies suggests a role for the cystic fibrosis transmembrane conductance regulator (CFTR) in apical epithelial bicarbonate conductance. Abnormal lumenal acidification is thus hypothesized to play a role in the genesis of cystic fibrosis (CF) pancreatic disease. However, consensus regarding CFTR's participation in p...

Inhalational insulin was withdrawn from the market due to its potential to produce airway hyper-reactivity and bronchoconstriction. So, the present study was designed to explore the acute effects of insulin on airway reactivity of guinea pigs and protective effects of salbutamol and ipratropium against insulin induced airway hyperresponsiveness on isolated tracheal smooth muscle of guinea pig. ...

in this note first we define the notions of fuzzy positive implicativehyper bck-ideals of types 1,2,3 and 4. then we prove some theorems whichcharacterize the above notions according to the level subsets. also we obtainthe relationships among these notions, fuzzy (strong, weak, reflexive) hyperbck-ideals and fuzzy positive implicative hyper bck-ideals of types 5,6,7and 8. then, we define the no...

Asthma is a serious health and socioeconomic issue all over the world, affecting more than 300 million individuals. The disease is considered as an inflammatory disease in the airway, leading to airway hyperresponsiveness, obstruction, mucus hyper-production and airway wall remodeling. The presence of airway inflammation in asthmatic patients has been found in the nineteenth century. As the inf...