Bone morphogenetic proteins (BMPs) regulate various biological processes, mostly mediated by cells of mesenchymal origin. However, the roles of BMPs in epithelial cells are poorly understood. Here, we demonstrate that, in polarized epithelial cells, BMP signals are transmitted from BMP receptor complexes exclusively localized at the basolateral surface of the cell membrane. In addition, basolat...

Abstract Small-scale aquaculture systems can contribute significantly to food and nutritional security, poverty alleviation, rural development, especially in developing countries. However, the intensification of often has negative environmental outcomes. The adoption diversification practices (e.g. polyculture, pond-dike cropping (PDC)) better management (BMPs) been identified as a possible app...

The pattern of feather buds in a tract is thought to result from the relative ratios between activator and inhibitor signals through a lateral inhibition process. We analyse the role of Drm/Gremlin, a BMPs antagonist expressed during feather pattern formation, in the dermal precursor, the dense dermis, the interbud dermis and in the posterior dermal condensation. We have altered the activity of...

The present study examined the correlation between the level of activity neuron B52 and the transition from protraction to retraction phases of buccal motor patterns (BMPs) and the termination of the BMPs. The level of activity in B52 during the protraction phase was positively correlated with the duration of that phase. A second burst of activity in B52 was associated with the termination of t...

In 1978, the Wisconsin Legislature committed to protecting water quality by enacting the Nonpoint Source Water Pollution Abatement Program. Through this program, cost-share money is provided—within priority watersheds—to control sources of nonpoint pollution. Most of the cost-share dollars for rural watersheds have been used to implement barnyard Best Management Practices (BMPs) because barnyar...

The urbanization of agricultural lands is currently one of the dominant patterns of land use change in developed countries. In the United States and parts of Europe, this has led to the implementation of agricultural land preservation programs and riparian protection and replanting efforts along urban streams. The ecological benefits of such programs for the conservation of freshwater biodivers...

Transfer of nutrients from agriculture and wastewater to the hydrosphere attracts attention of policymakers and scientists due to an increasingly important influence on the water environment. Crop and livestock production and fisheries predominantly support the Myanmar economy. However, phosphorus (P), which is used in cultivation and is also present in domestic sewage, is a major source of bio...

Limb development, a complicated biological event that includes diverse processes such as three-dimensional patterning, cartilage and bone differentiation and programmed cell death, or apoptosis, is regulated by a network of signal molecules that work in concert to ensure proper morphogenesis. Bone Morphogenetic Proteins (BMPs), members of the TGF superfamily, play a pivotal role in the signalin...

The regeneration of bone is a remarkable, complex physiological process, and BMPs are a formidable clinical tool to promote its regeneration. By defining roles played by BMPs in developmental biology and bone regeneration, significant progress has been made to identify cell-signaling molecules and their regulators. For example, the regulators of BMPs that include noggin, chordin, cerberus, dan,...