The United States Public Health Service Administration is alerting medical professionals that a substantial percentage of cocaine imported into the United States is adulterated with levamisole, a veterinary pharmaceutical that can cause blood cell disorders such as severe neutropenia and agranulocytosis. Levamisole was previously approved in combination with fluorouracil for the treatment of co...

Sodium metamizole (SM), analgin, was recalled from the pharmaceutical market by regulatory authorities of some countries in mid-60s because side effects (agranulocytosis). However, there has been a trend towards steady increase its prescription rates recent decades. The aim study to characterise status SM different world, assess effectiveness and safety, analyse available data on medication err...

Sir, This is in response to the article' Do Indian researchers read Indian research? a reappraisal, four years later', published in April 2000 (No.2, f Vol.42) issue of your journal. The authors of this article have documented their observations on my article 'Transsexualism in Schizophrenia : a case report' (April, 1998, Vol.40, No.2) that I did not refer to their article, 'Behaviour Therapy f...

BACKGROUND Antithyroid drugs (ATDs) can lead to the development of agranulocytosis, which is the most serious adverse effect. Characteristics of ATD-induced agranulocytosis (AIA) have seldom been reported due to the rarity. In this study, we characterized the clinical features for AIA in Korean patients. METHODS We retrospectively reviewed data from patients with AIA diagnosed between 1997 an...

BACKGROUND: Drug-induced agranulocytosis, a severe side effect marked by a deficit or absolute lack of granulocytic white blood cells, is a rare side-effect of the anti-inflammatory drug sulphasalazine. Mutations in the human neutrophil elastase gene (ELA2), causing increased intracellular concentration of this serine protease, inhibits neutrophil differentiation in severe congenital neutropeni...

To cite: Khan U, Hadid T. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2017-219403 DESCRIPTION A Caucasian woman aged 74 years successfully underwent laminectomy and decompression surgery for spinal stenosis, which was complicated by wound infection with community-acquired methicillin-resistant Staphylococcus aureus (MRSA), MRSA bacteraemia and endocarditis. M...

THE clinical features of agranulocytosis, and the frequent (levelopment of the condition following the administration of pyramidon, are now widely recognized. The folloxving case is sufficiently typical to be worth recording:Mrs. E. W., aged 53. Seen with Dr. J. Unsworth on 2nd April, 19:36. There was a history of about one week's illness with a "septic throat," pyrexia, vomiting, and occasiona...