OBJECTIVES Steroids may raise the blood glucose levels as a systemic effect. Due to this, the potential effect of prophylactic use of inhaled steroids (ICS) on HbA1c levels in children with asthma was investigated. STUDY DESIGN Case control study. ? SETTING Outpatient department. PARTICIPANTS 141 children with asthma but without diabetes (study group) and 52 children without diabetes or a...

OBJECTIVE This study aimed to investigate the expression of miR-200c and miR-141 in glioma tissues and cell lines and then to study their regulative effect on ZEB1 expression and on glioma cell growth and migration. MATERIALS AND METHODS QRT-PCR analysis was performed to detect miR-200c and miR-141 expression in 10 paired glioma tissues and adjacent normal tissues from patients with glioblast...

BACKGROUND The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/P...

OBJECTIVE To examine the prevalence of the metabolic syndrome and the relationship between metabolic syndrome score (MetS score) and disease characteristics and cardiovascular events (CVEs) in women with SLE. METHODS Demographic and clinical data were collected in 141 female SLE patients. The prevalence of the metabolic syndrome was defined by a modified National Cholesterol Education Program...

The April-June 2006 edition of JSLS contained 2 disturbing papers addressing technical aspects of vascular control in laparoscopic donor nephrectomies. Lallas et al report an algorithm developed during a series of 200 cases performed at the Mayo Clinic in Scottsdale, Arizona in which “early vessel branching or a potential for inadequate vessel length” prompted the use of Hem-o-lok clips on the ...

BACKGROUND The association between Helicobacter pylori infection and gastric cancer has been identified recently. However, the molecular mechanism remained largely unknown. METHODS AND RESULTS We found that miR-141 was decreased in Helicobacter pylori positive specimens (n=75) compared with negative tissues (n=75). The knockdown of miR-141 enhanced the invasion ability of gastric cancer cells...

Background: Temporomandibular disorders (TMD) relate to dysfunctions that impact the temporomandibular joint (TMJ), masticatory muscles, and connected structures. Psychological well-being can be among various factors TMD affects. Prior studies conducted in different countries have demonstrated a correlation between symptoms psychological distress young adults. However, research on this topic is...