Aeromonas is recognized to cause a variety of diseases in man. In humans, they are associated with intestinal and extra-intestinal infections. With the growing importance of Aeromonas as an emerging pathogen, it is important to combat this organism. It is indisputable that Aeromonas strains may produce many different putative virulence factors such as enterotoxins, hemolysins or cytotoxins, and...

Natterin is an aerolysin-like pore-forming toxin responsible for the toxic effects of venom medically significant fish Thalassophryne nattereri. Using a combination pharmacologic and genetic loss-of-function approaches we conduct systematic investigation regulatory mechanisms that control Natterin-induced neutrophilic inflammation in peritonitis model. Our data confirmed capacity to induce stro...