نتایج جستجو برای: aerobic cell

تعداد نتایج: 1713074  

Journal: :Cell 2015
Ping-Chih Ho Jessica Dauz Bihuniak Andrew N. Macintyre Matthew Staron Xiaojing Liu Robert Amezquita Yao-Chen Tsui Guoliang Cui Goran Micevic Jose C. Perales Steven H. Kleinstein E. Dale Abel Karl L. Insogna Stefan Feske Jason W. Locasale Marcus W. Bosenberg Jeffrey C. Rathmell Susan M. Kaech

Activated T cells engage aerobic glycolysis and anabolic metabolism for growth, proliferation, and effector functions. We propose that a glucose-poor tumor microenvironment limits aerobic glycolysis in tumor-infiltrating T cells, which suppresses tumoricidal effector functions. We discovered a new role for the glycolytic metabolite phosphoenolpyruvate (PEP) in sustaining T cell receptor-mediate...

Journal: :Cell 2016
Michael D. Buck David O’Sullivan Ramon I. Klein Geltink Jonathan D. Curtis Chih-Hao Chang David E. Sanin Jing Qiu Oliver Kretz Daniel Braas Gerritje J.W. van der Windt Qiongyu Chen Stanley Ching-Cheng Huang Christina M. O’Neill Brian T. Edelson Edward J. Pearce Hiromi Sesaki Tobias B. Huber Angelika S. Rambold Erika L. Pearce

Activated effector T (TE) cells augment anabolic pathways of metabolism, such as aerobic glycolysis, while memory T (TM) cells engage catabolic pathways, like fatty acid oxidation (FAO). However, signals that drive these differences remain unclear. Mitochondria are metabolic organelles that actively transform their ultrastructure. Therefore, we questioned whether mitochondrial dynamics controls...

Journal: :Fen-mühendislik dergisi 2023

A microbial fuel cell (MFC) with cathode and anode chambers was utilized to generate power while simultaneously removing COD from wastewater. By utilizing various oxidant solutions, it is possible increase the generated voltage. The chamber used for anaerobic treatment of synthetic wastewater (approximately 1000 mg/L), whereas contained solutions such as dilute hydrogen peroxide (300 KMnO4 K2Cr...

Journal: :Journal of bioscience and bioengineering 2000
K Asami Y Tanji H Unno

Infection of Escherichia coli cells by T4 phage at a multiplicity of infection (MOI) of 0.01 caused inhibition of cell lysis for up to 4 h. Such cells grown under aerobic condition were lysed by external stimuli such as cold shock, osmotic shock or addition of toxic substances, e.g., carbonyl cyanide m-chlorophenylhydrazone (CCCP). However, the effects of these external stimuli were reduced by ...

Journal: :ACS Applied Materials & Interfaces 2021

Reliable and accurate in situ sensors capable of detecting quantifying troublesome marine biofilms on metallic surfaces are increasingly necessary. A 0.2 mm diameter gold electrochemical sensor was fully characterized using cyclic voltammetry abiotic biotic artificial seawater media within a continuous culture flow cell to detect the growth development an aerobic Pseudoalteromonas sp. biofilm. ...

Journal: :Cancer research 1981
A M Rauth J K Mohindra

The chemotherapeutic agent 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC) is used in the treatment of malignant melanoma where response rates of 15 to 30% have been reported. Some current interest exists in combining DTIC chemotherapy with localized high-dose (800 rads)-per-fraction radiotherapy in the treatment of unresectable metastatic melanoma. The present work investigates the ...

Journal: :The Biochemical journal 2009
Guoqiang Tan Jianxin Lu Jacob P Bitoun Hao Huang Huangen Ding

IscA/SufA paralogues are the members of the iron-sulfur cluster assembly machinery in Escherichia coli. Whereas deletion of either IscA or SufA has only a mild effect on cell growth, deletion of both IscA and SufA results in a null-growth phenotype in minimal medium under aerobic growth conditions. Here we report that cell growth of the iscA/sufA double mutant (E. coli strain in which both iscA...

2012
Amy Boyd Celeste T Yang Kim Estell Craig Tuggle MS Lynn B Gerald Mark Dransfield Marcas Bamman James Bonner T Prescott Atkinson Lisa M Schwiebert

BACKGROUND Aerobic exercise appears to have clinical benefits for many asthmatics, yet a complete understanding of the mechanisms underlying these benefits has not been elucidated at this time. PURPOSE The objective of this study was to determine feasibility for a larger, future study that will define the effect of aerobic exercise on cellular, molecular, and functional measures in adults wit...

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