We have studied the urinary excretion of free and acetylated polyamines in hepatoma-bearing Buffalo rats during the period of linear growth of the tumor mass. The excretion of nonconjugated polyamines was unchanged. N1-Acetylspermidine excretion did not parallel the linear increase in tumor mass but increased exponentially. Enhancement of N8-acetylspermidine excretion above control levels was o...

We study the relationship between the sizes of two-way finite automata accepting a language and its complement. In the deterministic case, for a given automaton (2dfa) with n states, we build an automaton accepting the complement with at most 4n states, independently of the size of the input alphabet. Actually, we show a stronger result, by presenting an equivalent 4n-state 2dfa that always hal...

Reaction of N3,N8-diacyl 6-thia-3,8-diazabicyclo/3.2. l./octan-2-one (I) with PC15 or S02Cl2 gave 6-chloro substituted N2,N5-diacyl 7-thia-2,5-diazabicyclo/2.2.2./octan-3-one (II). Treatment of II with water yielded the 6-hydroxy derivative (III) while reaction with methanol gave the 6-methoxy derivative (IV). Under the same reaction conditions the mono N8-acyl derivative (V) gave a mixture of ...

Carum carvi (CC) is a grassy plant which is believed to have several therapeutic effects, including anti-asthmatic properties. We have therefore studied the bronchodilatory and anticholinergic effects of this plant. The bronchodilatory effects of the aqueous extract (AE), macerated extract (ME), essential oil (EO), and 4µM theophylline (T) in comparison with saline (S) were examined by the...

The current–voltage characteristics I(V) of model organic devices are studied under ultra-high-vacuum conditions. Active materials are N,N8-bis-(1-naphthyl)-N,N8-diphenyl1-1,1-biphenyl1-4,48-diamine ~a-NPD! and pentacene, electrode materials are polycrystalline Au and the conductive polymer poly~3,4-ethylenedioxythiophene!/poly~styrenesulfonate! ~PEDOT/ PSS!. Despite a similar work function of ...

Role of asparagine-linked (N-linked) oligosaccharide side chains in the maturation and the function of influenza virus neuraminidase (NA) subtype N8 was examined by site-directed mutagenesis and vaccinia virus expression system. Mutations in the consensus sequence for N-linked glycosylation at Asn 84 or 398 prevent the proper maturation of mutant NAs. On the contrary, mutation at Asn 144, that ...

In the present study, 78 lactic acid bacteria (LAB) strains were screened for the antagonistic activity against Campylobacter jejuni and 15 LAB strains with high bactericidal capacity were selected for further study through the analysis of the inhibition zone of LAB spent culture supernatant on the growth of C. jejuni. Among these strains, four isolates, Lactobacillus plantarum N8, N9, ZL5 and ...