objectives: leptin is a hormone-like protein produced by the adipose tissue. it plays an important role in protection of host against inflammation and infection. some studies have reported changes in leptin levels in the gingival crevicular fluid (gcf), saliva and blood serum of patients with periodontal disease compared to healthy individuals. the aim of the present study was to compare the sa...

At the "International Workshop for a Classification of Periodontal Diseases and Conditions" in 1999, the classification of periodontal diseases was revised (Armitage 1999). The various types of periodontitis were divided into three main categories (chronic, aggressive, and necrotizing periodontitis) as well as into a periodontal a manifestation of systemic diseases. This article provides a syno...

BACKGROUND Several studies have shown that periodontal diseases are associated with hypertension (HT). However, heterogeneity among populations, diagnosis criteria, and shared risk factors represent some difficulties in terms of interpretation. Therefore, the aim of this study was to determine the magnitude of the association between periodontal diseases and HT. METHODS AND RESULTS A systemat...

Periodontal diseases, is the infection of periodontal tissues which eventually can lead to loss teeth, a form aberrant inflammation resulting from complex biofilm friendly commensal and periodontopathic bacteria their products, triggering human inflammatory response.

Periodontitis and rheumatoid arthritis (RA) appear to share many pathologic features. In this review, the common pathologic mechanisms of these two common chronic conditions are explored. Emerging evidence now suggests a strong relationship between the extent and severity of periodontal disease and RA. While this relationship is unlikely to be causal, it is clear that individuals with advanced ...

The regeneration and integration of multiple tissue types is critical for efforts to restore the function of musculoskeletal complex. In particular, the neogenesis of periodontal constructs for systematic tooth-supporting functions is a current challenge due to micron-scaled tissue compartmentalization, oblique/perpendicular orientations of fibrous connective tissues to the tooth root surface a...

AIM The primary aim of the study was to systematically map registration records on periodontal medicine in clinical trial registers. The secondary aim was to assess the evolution of periodontal medicine in clinical periodontal research as a whole. MATERIAL AND METHODS We searched all registration records related to periodontology in the World Health Organization International Clinical Trials ...

For ten years, the incidence of preterm birth does not decrease in developed countries despite the promotion of public health programs. Many risk factors have been identified including ethnicity, age, tobacco, and infection. However, almost 50% of preterm birth causes remain unknown. The periodontal diseases are highly prevalent inflammatory and infectious diseases of tooth supporting tissues l...

OBJECTIVE To review recent data on the nature and pathobiology of periodontal infections and to elaborate how periodontal infections might increase susceptibility to some important systemic diseases and conditions. DATA SOURCES Medline literature search and websites of the American Academy of Periodontology and American Medical Association. STUDY SELECTION Literature and data on periodontal...