نتایج جستجو برای: adult csf
تعداد نتایج: 328972 فیلتر نتایج به سال:
Amyotrophic lateral sclerosis is not only a motor neuron disease: impact of the sympathoadrenal axis
Amyotrophic lateral sclerosis (ALS), an adult onset, fatal neurodegenerative disease, has as a cardinal pathogenic feature the selective death of motor neurons (MNs) at cortex, brainstem, and spinal cord. In this review we focus on four aspects: (i) hypothesis disease propagation through cerebrospinal fluid (CSF); (ii) distortion exocytotic release neurotransmitters sympathoadrenal axis; (iii) ...
Objective To evaluate the relationship between circulating phenylalanine and brain function as well neuropsychiatric symptoms in adults with phenylketonuria. Methods In this prospective cross-sectional study, early-treated patients phenylketonuria older than 30 years age- sex-matched controls were included. Extensive neurologic evaluation, neuropsychological behavioral testing, sensory motor ev...
میزان نشو و نما و قدرت باروری شبپره ی مدیترانه ای آرد 2) جوانه ی ) ،(fb) ( رژیم غذ ایی تهیه شده از ( 1) آرد گندم + سبوس گندم ( 75 درصد و 25 درصد 3) جوانه ی گندم + ) ،(myg) ( گندم + مخمر نان + گلیسرول به نسبت ( 10 به 1 به 2 وزن به وزن 4) سبوس گندم + مخمر نان + گلی سرول ( 20 به 1 به 2 ) ،(my) ( مخمر نان ( 10 به 1 وزن به وزن و ( 5) سبوس گندم + مخمر نان + گلیسرول + آب ( 100 به 5 به 10 به 5 وزن ...
in this study demographic, clinical, paraclinical, microbiological, and therapeutic features of patients with community-acquired acute bacterial meningitis admitted to a referral center for infectious diseases in iran, have been evaluated. medical records of adult (> 18 years) individuals with confirmed diagnosis of community-acquired bacterial meningitis during a 4-year period were retrospecti...
Adult hippocampal neurogenesis is a remarkable form of brain plasticity through which new neurons are generated throughout life. Despite its important roles in cognition and emotion and its modulation in various preclinical disease models, the functional importance of adult hippocampal neurogenesis in human health has not been revealed because of a lack of tools for monitoring adult neurogenesi...
We provide comprehensive identification of embryonic (E15) and adult rat lateral ventricular choroid plexus transcriptome, with focus on junction-associated proteins, ionic influx transporters and channels. Additionally, these data are related to new structural and previously published permeability studies. Results reveal that most genes associated with intercellular junctions are expressed at ...
BACKGROUND Recent research has demonstrated that circulating peripheral blood mononuclear fractions (PBMC) containing haematopoietic stem (HSC)/progenitor cells have the potential to play a crucial role in regenerative medicine strategies. Work in our laboratory has shown that a peripheral blood mononuclear cell fraction (PBMC) enhances cartilage repair in an osteochondral defect model in sheep...
The central nervous system (CNS) pharmacokinetics of the H(1) receptor antagonist diphenhydramine (DPHM) were studied in 100- and 120-day-old fetuses, 10- and 30-day-old newborn lambs, and adult sheep using in vivo microdialysis. DPHM was administered i.v. at five infusion rates, with each step lasting 7 h. In all ages, cerebrospinal fluid (CSF) and extracellular fluid (ECF) concentrations were...
Adult rhesus monkeys were given 2-mg/sq m i.v. bolus injections of radiochemically pure tritiated vincristine (VCR). Simultaneous specimens of blood and cerebrospinal fluid (CSF) were sampled from 5 min to 72 hr following injection. CSF was obtained from Ommaya reservoirs which had been implanted s.c. in each monkey. VCR and its metabolic and/or decomposition products rapidly entered the CSF pr...
Neonates, especially those of very low birthweight (VLBW), have an increased risk of nosocomial infections secondary to deficiencies in development. We previously demonstrated that granulocyte-macrophage colony-stimulating factor (GM-CSF) production and mRNA expression from stimulated neonatal mononuclear cells are significantly less than that from adult cells. Recombinant murine GM-CSF adminis...
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