introduction: it has been demonstrated that the adrenal medullary transplants into the spinal subarachnoid space can alleviate neuropathic pain behaviors. the aim of the present study was to test the possibility that histological changes of the sciatic nerve in a neuropathic model as well as sensory dysfunction are repaired by adrenal medullary transplantation. material and methods: left sciati...

background: noise pollution is considered as a stressful factor in every day’s life of the industrial world. the present study was designed to investigate the probable effects of different time exposure of noise stress on histomorphometric changes of adrenal gland, plasma cortisol and body weight of the rat.   methods: sixty adult male wistar rats were divided into two series of short time nois...

background: congenital adrenal hyperplasia (cah) and vanishing testes are uncommon diseases that can result from hormonal and mechanical factors. classic cah is determined by ambiguous genitalia and increase in amount of 17-hydroxyprogesterone. simultaneous occurrence of cah and vanishing testes is a rare condition. case: a 22-year-old boy, known case of cah who was diagnosed as female pseudohe...

primary adrenal insufficiency (addison’s disease) is due to adrenocortical disease. this study is about a 40 year old man who had been referred to a hematologist who assessed him for anemia. he  had been affected by a periodic paresthesia one month prior to his visit to the physician. according to the clinical presentation, macrocytic anemia and hypersegmentation of pmn in pbs, bma/b was perfor...

background: adrenal hematoma is a very rare acquired cause of neonatal hypertension. in this study, we report a case of neonatal hypertension associated with adrenal hematoma. a male neonate was immediately transferred to our neonatal intensive care unit after delivery due to meconium aspiration. he needed to be on mechanical ventilation support. during his hospital stay, hospital records showe...

background medication is one of the supplementary steps in dental treatment. dentists prescribe medicine in order to avoid post-surgery complications. to the best knowledge of the researchers, no thorough study has been carried out to review the prescribed drugs in fars province, iran. objectives the current study aimed to determine the current status of the issue and compare it with global sta...

The cholesterol transfer function of steroidogenic acute regulatory protein (StAR) is uniquely integrated into adrenal cells, with mRNA translation and protein kinase A (PKA) phosphorylation occurring at the mitochondrial outer membrane (OMM). The StAR C-terminal cholesterol-binding domain (CBD) initiates mitochondrial intermembrane contacts to rapidly direct cholesterol to Cyp11a1 in the inner...

Whenever you face a difficult exam at school, may feel nervous and stressed. In these situations, your adrenal glands kick in. These are located on the tops of kidneys. The main job is to produce hormones, which molecules responsible for many functions in body. One hormones produced by called cortisol. Cortisol helps us manage stressful situations. However, some people’s bodies fail people suff...

background: congenital adrenal hyperplasia (cah, the inherited inability to synthesize cortisol) is one of the most common (1 in 10000 to 1 in 15000) autosomal recessive disorders. more than 95% of cases of cah are caused by 21-hydroxylase deficiency (21-ohd). females with severe, classic 21-ohd are exposed to excess androgens prenatally and are born with virilized external genitalia. most pati...