The latest estimates and analyses from the Global Burden of Disease Study 2015 (GBD 2015) provide a vital link between the Millennium Development Goals (MDGs) and the Sustainable Development Goals (SDGs) for 2016–30. The GBD 2015 investigators report global and national trends in various health metrics, from 1990 to 2015, and their association with levels of national development measured throug...

This study examines e-mail response latency as an expectancy violation, and explores its impact. Managers evaluated job candidates who varied in their response latency to an e-mail (one day, two weeks, and silence for over a month), and in their reward valence. As predicted by expectancy violations theory (Burgoon & Hale, 1988), candidate reward valence moderated the effect of response latency ...

BACKGROUND Life expectancy at birth as an alternative summary measure of mortality represents number of years which a newborn will be alive based on the current age specific death rates. As it summarizes death rates across all age range in a given population is the most common summary measure of mortality. The aim of this study was to correct death rates for underreport and estimate life expect...

Limited information exists about the consequences of hypertension during adulthood on residual life expectancy with cardiovascular disease. We aimed to analyze the life course of people with high blood pressure levels at age 50 in terms of total life expectancy and life expectancy with and without cardiovascular disease compared with normotensives. We constructed multistate life tables for card...

OBJECTIVES To evaluate the long-term cost-effectiveness of transferring type 2 diabetes patients to an insulin detemir regimen after failure to achieve adequate control with oral antidiabetic agents (OADs) alone, or in combination with neutral protamine hagedorn (NPH) insulin, or with insulin glargine in Germany. METHODS A computer simulation model of diabetes was used to make long-term proje...

INTRODUCTION Treatment with glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors, which target the incretin axis, has the potential to improve glycemic control in type 2 diabetes patients without the weight gain associated with traditional therapies. To evaluate the relative cost-effectiveness of incretin therapies, the present study aimed to compare the long-term cli...

Limited information exists about the consequences of hypertension during adulthood on residual life expectancy with cardiovascular disease. We aimed to analyze the life course of people with high blood pressure levels at age 50 in terms of total life expectancy and life expectancy with and without cardiovascular disease compared with normotensives. We constructed multistate life tables for card...

background cancer is one of the most important leading causes of morbidity and mortality worldwide. objectives this study aimed to calculate the burden of 9 common cancers in the population covered by mashhad university of medical sciences in iran in 2010-2011. patients and methods we calculated disability adjusted life years (dalys ) for each of nine cancers according to the sex and age groups...

objectives: each year, the united nations publishes an annual report titled by “human development report” for all countries around the world which in which the complex index for human development for achieving health life alongside education and economic welfare is examined. the innate ambiguity in estimation of human development index has brought about numerous criticism against the method of ...

Background and aims Lung cancer has the highest mortality rate of all cancers worldwide. Non-small-cell lung cancer (NSCLC) accounts for 85% of all lung cancers and has an extremely poor prognosis. Afatinib is an irreversible ErbB family blocker designed to suppress cellular signaling and inhibit cellular growth and is approved in Europe after platinum-based therapy for squamous NSCLC. The obje...