The adipose tissue is a source of inflammatory proteins, such as TNF, IL-6, and CXCL8. Most of their production occurs in macrophages that act as scavengers of dying adipocytes. The application of an orbital mechanical force for 6-10 min at 97 g to the adipose tissue, lipoaspirated and treated according to Coleman procedures, abolishes the expression of TNF-α and stimulates the expression of th...

M2 macrophages, innate lymphoid type 2 cells (ILC2s), eosinophils, Tregs, and invariant NK T cells (iNKT cells) all help to control adipose tissue inflammation, while M1 macrophages, TNF, and other inflammatory cytokines drive inflammation and insulin resistance in obesity. Stromal cells regulate leukocyte responses in lymph nodes, but the role of stromal cells in adipose tissue inflammation is...

background susceptibility-weighted imaging (swi) is extremely sensitive in the detection of superparamagnetic iron oxide (spio) nanoparticle-labeled cells. however, no study has compared molecular imaging for stem cell detection using swi and other mri pulse sequences. objectives this study aims to assess the sensitivity of swi in detecting spio nanoparticle-labeled, human bone marrow-derived m...

Human adipose tissue has been shown to contain a population of cells that possesses extensive proliferative capacity and the ability to differentiate into multiple cell lineages. These cells are referred to as adipose tissue-derived stem cells (ADSCs) and are generally similar, though not identical, to mesenchymal stem cells (also referred to as marrow stromal cells). ADSCs for research are mos...

introduction: dental pulp-derived mesenchymal stem cells (mscs) have emerged as a promising tool for use in regenerative medicine. the in vitro growth kinetic and culture requirement of the cells derived from human dental pulp, which is the subject of this present study, is poorly described. materials and methods: stem cells were derived from human third molar and then characterized. the in vit...

BACKGROUND Mesenchymal stem cells (MSCs) are ideal candidates for treatment of diseases. Amniotic membranes are an inexpensive source of MSCs (AM-MSC) without any donor site morbidity in cell therapy. Adipose tissue derived stem cells (ASCs) are also suitable cells for cell therapy. There is discrepancy in CD271 expression among MSCs from different sources. In this study, the characteristics...

objective(s): adipose derived stem cells (adscs) can be engineered to express bone specific markers. the aim of this study is to evaluate repairing tibia in animal model with differentiated osteoblasts from autologous adscs in alginate scaffold. materials and methods: in this study, 6 canine’s adscs were encapsulated in alginate and differentiated into osteoblasts. alkaline phosphatase assay (a...