نتایج جستجو برای: adenomatous polyps
تعداد نتایج: 17789 فیلتر نتایج به سال:
Turcot syndrome is an autosomal recessive disorder clinically characterized by the occurrence of primary tumors of the central nervous system and adenomatous colonic polyps during the first or second decades of life, with a spectrum of clinical features such as "café-au-lait" spots, axillary freckling, and hyperpigmented spots. Currently its prevalence globally and in Colombia remains unknown. ...
Multiple intestinal neoplasia (Min) mice were originally identified by Moser et al. Min mice have a heterozygous mutation in the tumor suppressor gene, adenomatous polyposis coli (Apc). The APC gene is mutated in familial adenomatous polyposis (FAP). Min mice spontaneously develop intestinal polyps, similar to humans, but mainly in the small intestine. Polyps form as early as approximately 4 we...
Familial Adenomatous Polyposis (FAP) is the most common adenomatous polyposis syndrome, in which patients develop hundreds to thousands of polyps at an early age. The high number significantly increases risk their progression colorectal cancer (CRC). To investigate development and mechanism FAP, we used APC1311 mutant pigs our recent research has revealed that a significant proportion these und...
BACKGROUND AND STUDY AIMS Sessile serrated adenoma/polyps (SSA/Ps) have a different potential than traditional adenomatous polyps for developing into malignant colorectal cancer. However, little is known about the coexistent cancer rate. Here, we evaluate the frequency of carcinoma in serrated polyps removed by endoscopic resection (ER). PATIENTS AND METHODS This was a retrospective single-ce...
Most epidemiological evidence supports the inverse association between use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) and colorectal cancer. Few studies have investigated the relation between use of aspirin and other NSAIDs and adenomatous polyps, which are recognized as precursors of colorectal cancer. We examined the association of adenomatous polyps and the dose and d...
BACKGROUND Colorectal cancer (CRC) (adenomatous, adenocarcinoma) is one of the major causes of mortality and morbidity in human societies. Considering the importance of cyclooxygenase-2 (COX-2) expression in the incidence of CRC, in this study, the rate of COX-2 gene expression on polyps and CRCs were addressed. MATERIALS AND METHODS This is a cross-sectional descriptive analytic study carrie...
PURPOSE Endoscopic treatment of sessile and semipedunculated polyps remains controversial. Residual tissue remains frequently after endoscopic snare polypectomy. The aim of the study was to assess the outcome and safety of argon plasma coagulation (APC) in the management of gastric and colorectal polyp remnants after polypectomy, and to search for clinical parameters useful in predicting the ef...
BACKGROUND Colonic neoplasm is associated with western diet intake and physical inactivity. These life styles are also risk factors for dyslipidemia and metabolic syndrome. The aim of this study was to evaluate the association between dyslipidemia and the prevalence of colon polyps including colon adenoma as a precancerous lesion of colonic neoplasms. METHODS We selected subjects undergoing a...
CONTEXT The I1307K mutation of the APC gene is found in approximately 6% of the Ashkenazi Jewish population and is associated with elevated risk of colorectal cancer. The incidence of the mutation in patients with colorectal adenomas is unknown. OBJECTIVES To determine the carrier rate of the I1307K mutation in Ashkenazi Jewish patients with a history of colorectal polyps but without colorect...
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