Acute Toxicity Studies with Insect Attractants. BEROZA, M., INSCOE, M. N., SCHWARTZ, P. H., JR., KEPLINGER, M. L. AND MASTRI, C. W. (1975). Toxicol. Appl. Pharmacol. 31, 421-429. Eight insect attractants and one inhibitor of a sex attractant were tested for acute oral and aerosol inhalation toxicity in rats, for acute dermal toxicity, eye irritation, and primary skin irritation on rabbits, and ...

the acute toxicity of salts of alkali and alkaline earth metals, such as sodium (na), potassium (k), calcium (ca) and magnesium (mg) were studied on the egg and larval stages of indian major carp labeo rohita (hamilton). the acute toxicity experiments were conducted followed by the range finding bioassay tests. the experiments were conducted in triplicates. the cumulative percentage of dead or ...

Acute and chronic toxicity of methyl red (untreated) was examined on a freshwater fish Poecilia reticulata, using indices viz; mortality, reduction in RBC counts and their morphological abnormality (poikilocytosis and anisocytosis). Similar studies (acute toxicity) were also made in physicochemically and biologically treated methyl red. Data comparison of these four indices revealed poikilocyto...

Background: Trachyspermum ammi is one of the prominent plant in traditional medicine of the east with several medicinal effects such as improvement of stomach disease, digestive disorder, diarrhea, hemorrhoid, bladder stones, respiratory disease and etc. Medicinal plants is one of the important reason of toxicity particularly in children and the elderly therefore, evaluation of the toxic effect...

Aim of the study: The present study was carried out to evaluate the safety of ethanolic extract of celtis timorensis (EECT) by acute and sub-acute toxicity studies. Materials and Methods: Acute toxicity study was conducted in mice by using OECD 425 guidelines whereas sub-acute toxicity study was carried out in rats by using OECD 407 guidelines. In the acute toxicity study, mice were administere...

In this research work, 2, 4-substituted oxazolone derivatives OXZ-1 to OXZ-5 were screened for antidiabetic activity at 200 and 400 mg/kg b.w. p.o. for 15 days in streptozotocin induced diabetic rats. Acute and sub-acute toxicity studies were performed as per OECD guideline Up and Down Procedure425 and 407. Clinical signs, body weight, hematological, biochemical and histopathological examinatio...

Atrazine is currently the most widely used herbicide in agriculture for the production of corn and other crops in the world. In the present research, the effect of acute and chronic toxicity of atrazine (herbicide) on blood biochemical indices of grass carp (Ctenopharhyngoden idella) an important species of commercial fish was studied. In acute toxicity, pollutant toxicity to fish was tested by...

BACKGROUND Determination of acute toxicity, expressed as median lethal dose (LD50), is one of the most important steps in drug discovery pipeline. Because in vivo assays for oral acute toxicity in mammals are time-consuming and costly, there is thus an urgent need to develop in silico prediction models of oral acute toxicity. RESULTS In this study, based on a comprehensive data set containing...

BACKGROUND The aim of the study was to evaluate toxicity after extremely hypofractionated radiotherapy (EHF-RT) using a non-isocentric robotic radiosurgery system for early stage prostate cancer. METHODS Eligibility criteria of this feasibility study were 50 - 84 years old, and low-risk to intermediate-risk disease. The prescribed dose to the iso-dose line of 95% of planning target volume was...