PURPOSE The present study defines genomic loci underlying coordinate changes in gene expression following retinal injury. METHODS A group of acute phase genes expressed in diverse nervous system tissues was defined by combining microarray results from injury studies from rat retina, brain, and spinal cord. Genomic loci regulating the brain expression of acute phase genes were identified using...

in this article, we evaluated 17 iranian soldiers who were exposed to mustard gas utilized by the iraqi forces in the war fronts. their clinical symptoms and signs, laboratory tests, and other parameters were carefully assessed, an attempt was made to identify a finding of prognostic significance, and patients who recovered from the acute phase were followed to determine possible long-term effe...

background: acute renal failure describes as a syndrome by rapid decline in the ability of the kidney to eliminate waste products, regulate acid–base balance, and manage water homeostasis. when this impairment is prolonged and entered chronic phase, erythropoietin secretion by this organ is decreasing and toxic metabolic accumulates and causes hematological changes include decrease of hct, mcv ...

During infection and inflammation there is a cascade of reactions that occurs in the host collectively known as the acute-phase response (APR).1 Besides alterations in acute-phase reactants (plasma proteins), the APR is also associated with changes in lipoproteins.2 Increasing evidence suggests that high density lipoproteins (HDL) are a critical part of the acute phase response (APR) of the inn...

introduction: we intended to assess the accuracy of re-expressed modification of diet for renal disease (mdrd) and cockcroft-gault (cg) equations to estimate glomerular filtration rate (gfr) in chronic kidney disease in two different etiologies of acute renal failure (arf): acute tubular necrosis (atn) and acute glomerulonephritis (agn). methods: patients admitted for arf or the patients compl...

A new four elements compact antenna array is presented and discussed to achieve enhanced phase resolution without sacrificing the array output power. This structure inspired by the Ormia Ochracea’s coupled ears. The analogy between this insect acute directional hearing capabilities and the electrically compact antenna array is used to enhance the array sensitivity to direction of arrival estima...

This report describes the purification of an acute phase reactant from acute phase rabbit serum, which endows normal serum with the properties of acute phase serum, insofar as LPS is concerned. The acute phase reactant is referred to as LPS-binding protein, or LBP. LBP was purified approximately 2,000-fold by chromatography of acute phase serum on Bio-Rex 70 and Mono-Q resins. The resulting pre...

background and objectives: previous studies have shown the antinociceptive effect of morphine in animal models, but the specific anti-pain consequence of the abuse drug in female animals is unclear. the present research showed the morphine antinociception in female wistar rats using formalin test. materials and methods: subjects were 40 female wistar rats purchased from pasteur institute of ira...

BACKGROUND In patients with cirrhosis, infection is frequent and a leading cause of death. This is secondary to various immunologic abnormalities in both the innate and the adaptive immune system. However, it remains unclear whether cirrhosis affects the inflammatory systemic component of the innate immunity, 'the acute phase response', mostly effectuated by the liver itself. We hypothesized th...