Transmembrane potential and active tension were measured in isolated segments of turtle aorta and inferior vena cava. Changes in tension were associated with action potentials, but the potentials had a different pattern in the two tissues. When the frequency of the action potentials increased, the contractions summated, resulting in a steadily maintained contraction.

A defining feature of glial cells has been their inability to generate action potentials. We show here that there are two distinct types of morphologically identical oligodendrocyte precursor glial cells (OPCs) in situ in rat CNS white matter. One type expresses voltage-gated sodium and potassium channels, generates action potentials when depolarized and senses its environment by receiving exci...

Long-term potentiation (LTP) requires postsynaptic depolarization that can result from EPSPs paired with action potentials or larger EPSPs that trigger dendritic spikes. We explored the relative contribution of these sources of depolarization to LTP induction during synaptically driven action potential firing in hippocampal CA1 pyramidal neurons. Pairing of a weak test input with a strong input...

Bioelectric activity in single cells of the moth myocardium has been measured in situ with intracellular microelectrodes with particular reference to the bizarre ionic medium which bathes the tissues. Resting potentials averaged 47 mv, inside negative with respect to outside, despite a value of 11 mv calculated on the basis of transmembrane potassium concentration gradients. Action potentials o...

29 Abstract: We investigated the properties of action potential after-potentials in cultured dorsal root ganglion neurones from neonatal rats using the whole cell patch clamp technique. The aims of this study were to characterize after-potentials and investigate the possible influences of Ca-induced Ca release (CICR) on neuronal excitability. The reversal potentials of action potential afterdep...