Background. Rosacea is a chronic skin disease, possibly following the neurogenic skin inflammation model. Neurokinin B, involved in the pathogenesis of Parkinson's disease, frequently coexisting with subsequent onset of rosacea, is an endogenous ligand of the tachykinin receptor 3 (TACR3). Methods. 128 rosacea patients and 121 matched controls were genotyped for rs3733631 by PCR-RFLP and analyz...

Heat, sun exposure, environmental factors and specific foods can trigger flares in rosacea. The exact etiology of rosacea remains unknown, but is likely multifactorial. Infectious agents, such as Demodex, have been hypothesized as causative agents. In one recent study, staphylococcus epidermidis was felt to play a role in pustular and ocular rosacea. Vascular instability and pilosebaceous unit ...

Rhinophyma is the most prevalent presentation of the phymatous subtype of rosacea. Rosacea subtypes include erythematotelangiectatic type (type 1), papulopustular rosacea (type 2), phymatous rosacea (type 3) and ocular rosacea (type 4).[1] Phymatous rosacea is characterized early by prominent follicular pores or patulous follicles with mild swelling while advanced disease reveals pronounced hyp...

Consumer self-reported sensitive skin has become more prevalent yet there is limited knowledge on exactly what and the attributes associated with skin. An online survey was conducted 1,000 participants in US two key objectives: 1) understand who sufferers are 2) their concerns experiences care products. insights most commonly perceived sensitivity triggers, symptoms, conditions were evaluated. ...

OBJECTIVE To evaluate the clearing and intensity of symptoms of rosacea 60 days after the treatment of Helicobacter pylori infection. DESIGN Randomized, double-blind, placebo-controlled clinical trial. SETTING The dermatology section of a large multispecialty clinic in the North Central United States. PARTICIPANTS Men and women older than 25 years with active signs of rosacea who tested p...

BACKGROUND Rosacea is a common inflammatory facial skin condition. Recent genetic and epidemiological studies have suggested pathogenic links between rosacea and gastrointestinal disorders, but data are limited. OBJECTIVES The objective was to investigate the association between rosacea and coeliac disease (CeD), Crohn disease (CD), ulcerative colitis (UC), Helicobacter pylori infection (HPI)...

Rosacea is a common dermatological condition that predominantly affects the central regions of the face. Rosacea affects up to 3 % of the world's population and a number of subtypes are recognized. Rosacea can be treated with a variety of antibiotics (e.g. tetracycline or metronidazole) yet no role for bacteria or microbes in its aetiology has been conclusively established. The density of Demod...

Rosacea is a frequent chronic inflammatory skin disease of unknown etiology. Because early rosacea reveals all characteristics of neurogenic inflammation, a central role of sensory nerves in its pathophysiology has been discussed. Neuroinflammatory mediators and their receptors involved in rosacea are poorly defined. Good candidates may be transient receptor potential (TRP) ion channels of vani...

Recently, diverse hematologic parameters have been used as an indicator of the presence or severity of inflammatory and cardiovascular diseases. Our aim was to investigate the ratios of neutrophils to lymphocytes (NL), monocytes to high-density lipoprotein (HDL) cholesterol (MHC), and platelets to lymphocytes (PL) in patients with rosacea in comparison with the control group and determine wheth...