This is a report of a case of Epstein-Barr virus (EBV) associated haemophagocytic syndrome in a 17 year old woman with antibody deficiency. For two years before this presentation, serology showed abnormally high titres to EBV early antigen, suggestive of persistent infection with EBV. She became acutely unwell with clinical features consistent with virus associated haemophagocytic syndrome (VAH...

BACKGROUND The risk of cytomegalovirus (CMV) infection in solid organ transplant recipients has resulted in the frequent use of prophylaxis with the aim of preventing the clinical syndrome associated with CMV infection. OBJECTIVES To determine the benefits and harms of antiviral medications to prevent CMV disease and all-cause mortality in solid organ transplant recipients. SEARCH STRATEGY ...

A 30-year-old Caucasian man was referred to eye casualty by his general practitioner (GP) with a two-day history of a widespread, rapidly progressing, blistering rash with ulceration, along with red painful eyes. It started with a ‘flu-like’ illness with symptoms of malaise and arthralgia for which the patient self-medicated with ibuprofen. After one day the rash began on the shaft of the penis...