The detailed investigation of a methanolic extract of aerial parts of Achillea nobilis resulted in the isolation of 10 flavonoids. A new C-glycosylflavone, luteolin-6-C-apiofuranosyl-(1'''-->2'')-glucoside, was isolated besides orientin, isoorientin, vitexin, isoschaftoside, luteolin-7-O-beta-glucuronide, luteolin-4'-O-beta-glucoside and quercetin-3-O-methyl ether and two rare flavonolglycoside...

The mitogen-activated protein kinase (MAPK) family, including extracellular signal-regulated kinase (ERK)1/2, c-Jun N-terminal kinase (JNK)1/2 and p38 MAPK, is known to be activated by ultraviolet (UV) radiation in melanocytes to regulate melanin production. Reactive oxygen species (ROS) play important roles in the pathway of ERK and JNK activation. It has been established that the essential oi...

Mathematical, fuzzy logic and artificial neural network modeling of extraction kinetics essential oil from aerial parts yarrow (Achillea millefolium L.) using ohmic-assisted hydrodistillation

Achillea wilhelmsii have been used in folk remedies. The relaxant effects of the extract of A. wilhelmsii on tracheal chains of guinea pigs were examined. The relaxant effects of four cumulative concentrations of the extract, theophylline and saline were examined by their relaxant effects on precontracted tracheal chains of guinea pig by KCl (group 1), 10 μM methacholine (group 2), incubated ti...

background: the aim of this study was to investigate the effect of methanolic extract of achillea millefolium l. (mea) on the antiproliferative activity of bleomycin on human prostate cancer and normal skin cells. materials and methods: human prostate cancer cell (du-145) and human non-malignant fibroblast cell (hfff2) were treated with mea at various concentrations ( 20, 100, 500, 1000 and 200...

conclusions these results indicate that a. kellalensis extracts exert potent anti-rotaviral activity only after viral adsorption. the two extracts from a. kellalensis showed a good selectivity index. also these results suggest that extracts prepared from the flowers of a. kellalensis may be potential anti-rotaviral agents in vivo and be useful in veterinary medicine. background achillea kellale...